Colorblindness and hemophilia are both X-linked traits in humans. Explain how a female who has a defective color vision gene on one X chromosome and a defective blood clotting gene causing hemophilia on the other X chromosome can be neither a hemophiliac nor colorblind? Please discuss the effect of Gene dosage compensation in your answer and in your answer describe the molecular process by which this occurs.

Colorblindness and hemophilia are both X-linked traits in humans. Explain how a female who has a defective color vision gene on one X chromosome and a defective blood clotting gene causing hemophilia on the other X chromosome can be neither a hemophiliac nor colorblind? Please discuss the effect of Gene dosage compensation in your answer and in your answer describe the molecular process by which this occurs.

Name: Colorblindness and hemophilia are both X-linked traits in humans. Expl
Uploaded: 2024-03-20T06:42:55.000Z
Channel: Bartleby
Description: Colorblindness and hemophilia are both X-linked traits in humans. Explain how a female who has a defective color vision gene on one X chromosome and a defective blood clotting gene causing hemophilia on the other X chromosome can be neither a hemophi

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter11: Genome Alterations: Mutation And Epigenetics

Section: Chapter Questions

Problem 16QP: Familial retinoblastoma, a rare autosomal dominant defect, arose in a large family that had no prior...

See similar textbooks

Similar questions

Hemophilia is another example of an X-linked disease caused when a recessive allele (Xh) is expressed. If a normal male reproduces with a heterozygous normal female, what are the expected genotypes and phenotypes? Will any of their daughters develop hemophilia?
Describe when X-chromosome inactivation occurs and how thisleads to phenotypic results at the organism level. In your answer,you should explain why XCI causes results such as variegated coatpatterns in mammals. Why do two different calico cats have theirpatches of orange and black fur in different places? Explainwhether or not a variegated coat pattern due to XCI could occur inmarsupials.
Consider a couple: a woman who is homozygous for a recessive mutation that causes X-linked colorblindness, and a man with full color vision (he does not carry a copy of the mutation). a) What is the probability that a son of this couple will be colorblind? b) What is the probability that a daughter of the couple will be colorblind?
Suppose gene B is X-linked and is embryonically lethal when homozygous or hemizygous recessive. A man marries a woman who is heterozygous for this gene. They want to have three kids – one girl and two boys. Using a Punnett square, answer the following: What is the probability that they will have a son that dies before birth? _______________________ What is the probability that they will have a daughter who has the same genotype as her mother? _________________ One of their daughters eventually has a child with a man. One of their sons dies before birth. What was the genotype of this daughter? _______________________________ please show me how to get the answer and explain how you got and use a punnet square
Hemophilia is another example of a X-linked disease caused when a recessive allele (Xh) is expressed. If a normal male reproduces with a heterozygous normal female, what are the expected genotypes and phenotypes? Will any of their daughters develop hemophilia? As in the previous question, you must also give the gender of the child in your genotype and phenotype descriptions here.
The introduction to this chapter described the search for genes that determine pattern baldness in humans. In 1916, Dorothy Osborn suggested that pattern baldness is a sex-influenced trait that is dominant in males and recessive in females. More research suggested that pattern baldness is an X-linked recessive trait. Would you expect to see independent assortment between genetic markers on the X chromosome and pattern baldness if (a) pattern baldness is sexinfluenced and (b) if pattern baldness is X-linked recessive? Explain your answer.
Normal vision (XA) in humans is dominant to color blindness (Xa) and is X-linked. A man with normal vision, whose father was colorblind, marries a colorblind woman. What are the chances that a son will be colorblind? What are the chances that a daughter will be colorblind? The determiner for brown eyes (B) is dominant to blue eyes (b) and is not X-linked. A colorblind man with brown eyes, whose mother was blue-eyed, marries a blue-eyed woman having normal vision, whose father was colorblind. Show the expected phenotypes ratio of their children involving eye color, color blindness, and sex.
Hemophilia A is caused by a recessive X-linked allele that encodes a defective form of a clotting protein. If a affected father and a mother who is known to not be a carrier have children, what percentage of female offspring will have hemophilia?
The dosage of X chromosome expression is equalized between male and female mammals. Think about the example of calico cats to answer the following questions. Use Xb to represent the allele for black fur, XB to represent the allele for orange fur. What genotype(s) of female cats is/are expected to have a calico coat? Is it possible to have a calico cat that is male? Explain.
Duchenne muscular dystrophy is an X-linked, recessive disorder in which muscles waste away early in life, resulting in death in the teens or twenties. A man and woman in their late thirties have five children—three boys (ages 1, 3, and 10 years) and two girls (ages 5 and 7 years). The oldest, boy shows symptoms of the disease. What are the probabilities that their other children will develop the disease? Give only typing answer with explanation and conclusion
In humans, color vision depends on genes encoding three pigments. The R (red pigment) and G (green pigment) genes are close together on the X chromosome, whereas the B (blue pigment) gene is autosomal. A recessive mutation in any one of these genes can cause color blindness. Suppose that a color-blind man married a woman with normal color vision. The four sons from this marriage were color-blind, and the five daughters were normal. Specify the most likely genotypes of both parents and their children, explaining your reasoning. (A pedigree drawing will probably be helpful.) (Problem 50 is by Rosemary Redfield.)
In a particular country in sub-Saharan Africa, a medical study revealed that 0.075% of the country's population are suffering from sickle-cell anemia. Sickle cell disease is caused by a mutation in the haemoglobin-Beta gene found on chromosome 11. Sickle cell anemia is controlled by a pair of alleles, H and h, where the individuals with the illness have the homozygous recessive genotype; those with normal red blood cells have the alternative genotype. Using the Hardy-Weinberg's equation, calculate the percentage of the population of the two genotypes for normal blood cells. In a few remote areas in that country, the percentage of sickle cell anemia reaches as high as 5%. Calculate the percentage of homozygous and heterozygous individuals with the normal blood cells and find the ratio for both phenotypes.