Consider the reaction of two compounds ‘A’ and ‘B’ which could make two possible diastereomers ‘AB’ and ‘BA’ (much like this week’s Diels Alder reaction). Hand-write your calculations and responses to the following questions and upload your work as a .jpg or .pdf file. Which of the two products (A or B) will form in greater abundance under thermodynamic control? Which will form in greater abundance under kinetic control? Explain your responses using a sketch of the reaction coordinate diagram for the reactions described above.

Consider the reaction of two compounds ‘A’ and ‘B’ which could make two possible diastereomers ‘AB’ and ‘BA’ (much like this week’s Diels Alder reaction). Hand-write your calculations and responses to the following questions and upload your work as a .jpg or .pdf file. Which of the two products (A or B) will form in greater abundance under thermodynamic control? Which will form in greater abundance under kinetic control? Explain your responses using a sketch of the reaction coordinate diagram for the reactions described above.

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter8: Haloalkanes, Halogenation, And Radical Reactions

Section: Chapter Questions

Problem 8.34P

See similar textbooks

Similar questions

Uemura and coworkers studied a time dependent Diels-Alder reaction which first formed the endo product as the major organic product and with time produced the exo product (J. Org. Chem. 2018, 83, 9300−9304). Show the endo and exo product for the reaction below. Which is the thermodynamic product and which is the kinetic product? Explain your reasoning.
. Discuss the truth of the following statement. Explain why it is true or false Every SN1 reaction produces racemic mixtures in the products
give some real life application of stereochemistry
A chemist is attempting to synthesize a complex natural product with a highly strained cyclohexene ring system. Which type of reactants would be most suitable for achieving this goal, and why? Provide a detailed explanation of the choice of reactants and the expected outcome in terms of the Diels-Alder reaction.
Although benzene is normally written with three double bonds, benzene is not reactive towards many reagents that alkenes normally react with. This lack of reactivity can be explained by the unusual stability created by cyclic conjugation. First, (i) describe at least one of the physical properties of benzene that demonstrates how the true structure of benzene does match the way the structure is normally written. Then, (ii) explain how the unusual stability of benzene can be demonstrated by its thermodynamic properties through some form of experiment. Be sure to (iii) include an appropriately labeled diagram as part of your answer (you do not have to quote any numerical values).
This reaction is also an important reaction of the tricarboxylic acid cycle in cells, wherein the reaction occurs in neutral solution, so the acid groups are both ionized to the carboxylate form. The reaction is catalyzed by the stereospecific enzyme fumarase that utilizes only the trans form of 2-butenedioate ion (also known as fumarate) and produces only the (S)-2-hydroxysuccinate enantiomer (also known as (S)-malate). Draw the correct stereochemical structures of these two compounds of the fumarase-catalyzed reaction. Be sure to include all hydrogen atoms and show the carboxylates as anions.
Imagine that phenol (“hydroxybenzene”) and nitrobenzene are reacted (in separate beakers) with a hot solution containing both concentrated sulfuric acid and concentrated nitric acid. A) When chlorobenzene reacts with a hot solution of sulfuric and nitric acids, an interesting result occurs: the reaction is slower than the reaction of the solution with benzene – which is similar to the result of the reaction of the solution with nitrobenzene – but it generates products with the same substitution pattern seen in the reaction of the solution with phenol. Explain why chlorobenzene has this curious reactivity.
In the reactions given below, write to which organic molecule Y, Z, T, A ‘belongs, and give information about the reaction types that take place.
APPLY STEREOCHEMISTRY WHEN APPLICABLE: Does each reaction occur from SN1 or 2? What are the organic products?
) PLA, a polyester-based synthetic polymer, decomposes in our body fluid and separates into its constituent acids and alcohol. This acid in the body can cause inflammation. What would you recommend to overcome this disadvantage? b) The late decomposition of PLA, which is a biodegradable and hydrophobic polymer, in body fluid may create a disadvantage in applications where faster degradation is desired. What would you suggest to do to resolve this situation? Please explain.
give explanation in detail
I'm curious, can a decyclization or some chemical reaction to eliminate sulfur take place here, possibly forming SO2? and besides that, I would like you to give me examples of deciclizations of heterocycles, if they are possible, I honestly don't know