CRISPR-Cas9 is used by bacteria as a type of immune system against invading viruses. In recent years, it has been developed into a revolutionary tool that can induce double-stranded breaks at very specific locations in DNA in eukaryotic cells. CRISPR-Cas9 activity typically results in indel mutations in the targeted gene. Which DNA repair system most likely caused these indels? a) non-homologous end-joining b) mismatch repairc) nucleotide-excision repaird) base-excision repair e) homology-directed repair

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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CRISPR-Cas9 is used by bacteria as a type of immune system against invading viruses. In recent years, it has been developed into a revolutionary tool that can induce double-stranded breaks at very specific locations in DNA in eukaryotic cells. CRISPR-Cas9 activity typically results in indel mutations in the targeted gene. Which DNA repair system most likely caused these indels?

a) non-homologous end-joining

b) mismatch repair
c) nucleotide-excision repair
d) base-excision repair

e) homology-directed repair

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