What enzyme(s) control the total levels of cGMP in a cell? Is guanylyl cyclase one of the enzymes?
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What enzyme(s) control the total levels of cGMP in a cell? Is guanylyl cyclase one of the enzymes?
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- How is PKA activity regulated?During stressful situations, some cells in the body convertglycogen to glucose. What effect does this conversion haveon cellular osmotic balance? Explain how cells handle thissituation.Phospholipase A2 causes the release of what fatty acid from membrane phospholipids? What chemical class of messengers is produced from this fatty acid?
- How is the ability to store glucose as glycogen related to the general principle of physiology that physiological processes require the transfer and balance of matter and energy?In what disease is a decrease in sphingomyelin observed?There is a relatively high concentration of phosphatidylcholine on the lumenal side of the ER membrane. What feature of membranes is responsible for this effect?
- If the concentration of cholesterol is low, how might a cell that requires cholesterol respond?Fatty acids must associate with lipid chaperones in order to move within the cell. Why are these chaperones needed, and what is the name given to a group of proteins that are responsible for this intracellular trafficking of fatty acids? What is the key distinguishing feature of these proteins that allows fatty acids to move within the cell?Why does the lack of glucose 6- phosphatase activity in the brain and muscle make good physiological sense?