Cytokine IL-12 IL-17 IL-18 IL-4 Mean ±s.d. (pg/ml) Patients 166.7+84.5 76.5 45.7 368.7+199.5 27.115.3 Controls 93.5+39.2 37.635.3 141.147.1 17.3±7.2 P value <0.001 0.002 <0.001 <0.05 Discuss the distribution of the cytokines shown in this study and relates them with the pathogenicity of SLE.
Cytokine IL-12 IL-17 IL-18 IL-4 Mean ±s.d. (pg/ml) Patients 166.7+84.5 76.5 45.7 368.7+199.5 27.115.3 Controls 93.5+39.2 37.635.3 141.147.1 17.3±7.2 P value <0.001 0.002 <0.001 <0.05 Discuss the distribution of the cytokines shown in this study and relates them with the pathogenicity of SLE.
Chapter16: Adult And Pediatric Dosages Based On Body Surface Area
Section: Chapter Questions
Problem 7.4P
Related questions
Question
Transcribed Image Text:Plasma IL-12, IL-17, IL-18 and IL-4 concentrations of 36 Systemic Lupus Erythematosus
(SLE) patients were determined. Eighteen sex- and age-matched control subjects were
included. The cytokine concentrations were determined by enzyme linked immunosorbent
assay. The mean duration of the diagnosis of SLE at the time when patients were evaluated
for this study was 5.9-6.8 years. The results are shown in Table 1.
Table 1
Mean ±s.d. (pg/ml)
Cytokine
Patients
Controls
P value
IL-12
166.7±84.5
93.5土39.2
<0.001
IL-17
76.5±45.7
37.6±35.3
0.002
IL-18
IL-4
368.7±199.5
27.1±15.3
141.1土47.1
17.3±7.2
<0.001
<0.05
Discuss the distribution of the cytokines shown in this study and relates them with
the pathogenicity of SLE.
Expert Solution
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
Step by step
Solved in 3 steps with 9 images
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Recommended textbooks for you