Describe how targeted therapy effects the "Therapeutic window when Antibody drug conjugates are used . You can use a diagram to aid your explanation

Q: To probe for presence tubulin in protein samples by western blot you use a anti tubulin monoclonal…

A: A defense system in the body of an individual which constitutes a complex network of cells and…

Q: Define monoclonal antibodies and list some specificapplications of this technology.

A: The glycoproteins which are synthesized by the B cells differing in their amino acid sequence and…

Q: Explain the difference between in vivo and ex vivogene therapy.

A: It involves the supplementation of a defective gene with a functional allele. It is achieved by gene…

Q: Describe donor selection and blood processing, including assays for bloodborne infectious diseases.

A: Since you have asked multiple questions, we will solve the first question for you. If you want any…

Q: In treatment strategy 1, T cells collected from a cancer patient's relatives are trained to find and…

A: Cancer is a disease that poses a greater risk of causing death across the globe. There are several…

Q: Explain the effect of COM-blockers on bacterial transformation and their application in controlling…

A: Pathogens are disease-causing organisms that can cause humans to become ill or die depending on the…

Q: Which ethical issue is solved by induced pluripotent stem cells? Mention one advantage of using…

A: Induced pluripotent stem cells (iPSCs) are Artificial stem cells that are delivered from somatic…

Q: Show the chemistry involved in conjugating the drug (Calicheamicin-SH) to the antibody in Gemtuzumab…

A: mAb (monoclonal antibody) are antibodies which have monovalent affinity i.e., binding only one…

Q: Complement activation is a cascade reaction, with each component sequentially acting on others, in a…

A: The term that is  "complement cascade" is commonly refre to that they are been termed in the feild…

Q: The antimicrobial peptides (AMPs) are a special class of nonspecific cell-derived mediators with…

A: innate system of immunity is the first defense of the body . anti microbial peptides are part of the…

Q: What is “washing” in immunology? What types of interactions does washing interfere with? What…

A: Immunology is a branch of biology that covers the study of immune systems in all organisms. Immune…

Q: What are the advantages and disadvantages of drug delivery systems that are based on bacterial or…

A: A drug delivery system is a special form of drug delivery system where the medicament is selectively…

Q: sentences, Describe how the process of receptor desensitization leads to drug tolerance

A: Based on the agonist and the signaling route, desensitization is described as a slow but consistent…

Q: How Antiviral Drugs are made ? Explain how effective they are ?

A: Virus are the mcroorganisms that infects human and animals and thereby cause a variety of diseases,…

Q: Why would attaching an enediyne- containing molecule to an antibody be an attractive way to treat…

A: Enediynes are organic compounds that contain antitumor antibiotics. It contains two triple bonds and…

Q: If you are working in a diagnostic lab, what will be your choice among Monoclonal or Polyclonal…

A: Monoclonal antibodies are those specific type of antibody that only binds to a particular epitope…

Q: How could cyclosporine be used to treat autoimmune disease? be sure to explain you're reasoning

A: Answer- Cyclosporine works by weakening our immune system. White blood cells, part of our immune…

Q: What is monoclonal antibodies? How it can be categorized

A: Antibodies are Y-shaped protein molecules made by white blood cells (WBCs) in response to antigen.…

Q: Explain the steps involved in monoclonal antibody production using hybridoma technology.

A: Monoclonal antibodies are artificial antibodies designed to identify and bind to any antigens…

Q: Acyclovir can be used to treated virus-infected cells. Explain how?

A: Acyclovir is an antiviral medication which  is primarily used for the treatment of viral disesases…

Q: Design a laboratory protocol to develop a monoclonal or polyclonal antibody against a protein of…

A: Antibodies, also known as immunoglobulins, are protein molecules produced by the body's immune…

Q: Explain the two major classes of biologic response–modifying drugs: hematopoietic drugs and…

A: We can say that the disease is a condition that is caused due to deviation from the normal. The…

Q: Mention the challenges and potential problems while targeting tumor cells by using monoclonal…

A: Cancer is a disease that is associated with uncontrolled division of cells and invasion of…

Q: Please outline the general steps you would take to test your hypothesis that SIN-47 works by…

A: Hypothesis: SIN-47 works by disrupting the interaction between LEK2 and JAK4.

Q: Observe the structure of antibodies below that has four protein subunits. Explain why we only see…

A: SDS-PAGE separates proteins primarily by mass because the ionic detergent SDS denaturates and binds…

Q: Part A: Give an example of when you would want to use a broad-spectrum antibiotic and when you would…

A: INTRODUCTION Antibiotics These are medicines that can inhibit the growth of microorganisms.

Q: Compare the two major classes of biologic response–modifying drugs: hematopoietic drugs and…

A: The disease is a condition that is caused due to deviation from the normal. The disease may be…

Q: What is the strategy in drug design to fight AIDS?

A: AIDS or acquired immunodeficiency syndrome is caused by the human immunodeficiency (HIV) virus. It…

Q: he "Vaccine Options" figure, under the "Antibody Preparation" heading, the term "antigen" is sed.…

A: COVID-19 is caused by a coronavirus called SARS-CoV-2. The coronavirus is an RNA virus that causes…

Q: Describe the cancer immunotherapy that won the Nobel Prize in 2018. Please include:  how they…

A: Immunotherapy is a treatment that uses certain parts of the immune system to fight diseases such as…

Q: a. Draw and label the different components of an antibody drug conjugate. Give examples of the…

A: Antibody Drug Conjugates are the class of drugs , which targets on cancerous cells. They are also…

Q: What are the different methods for developing modified release drug delivery system ? Discuss about…

A: Modified release means the sustained or controlled release of active ingredients of drugs taken…

Q: What is selective toxicity in the context of antibiotic chemotherapy? Support your answer with…

A: Introduction :- Antimicrobial chemotherapy is used to treat infectious diseases by fighting the…

Q: How are antibodies used as targeting molecules?  What are their advantages and disadvantages

A: There are many antibodies that are used for targeting specific antigen. These specific antibodies…

Q: Please explain "droplet based immunoassay(immune assay)". Including "single droplet generates one…

A: Immuno assay is a biochemical method in which the quantification of a macromolecule can be done…

Q: Why won’t in vitro results necessarily ensure clinical success

A: INTRODUCTION Antibiotic Sensitivity test done by Kirby-Bauer method shows sensitivity for…

Q: Using the diagram as a guide, briefl y explain how the three factors in drug therapy interact.

A: Introduction: The administration of medications to treat or prevent disease is known as drug…

Q: Which of these antibiotics would do the best job as a broad spectrum antibiotic?

A: Broad spectrum antibiotic  These antibiotics have effect on numerous different type of bacteria and…

Q: As shown , several medical agents are now commercially produced by genetically engineered…

A: Genetically modified organisms play an important role in increasing the production of crops. Crops…

Q: In relation to immunotechnology, answer the following:Give ONE main difference between: Murine MABs…

A: MONOCLONAL ANTIBODY Monoclonal antibodies (MABs) are antigen-recognizing glycoproteins that are made…

Q: You want to detect troponin in an immunoblot. Give an example of a potential primary rabbit antibody…

A: Immunoblotting is a sensitive and rapid assay to detect and characterize proteins. It works by…

Q: If the cancer vaccine can elicit an inmmune response against the targets found on tumor cells, is…

A: The vaccinations are intended to identify proteins in cancer cells.Antigens are compounds that cause…

Q: Give examples of drug that is developed resistance? explain at your own words

A: The reduced efficacy of drug such as antimicrobial to treat a disease is known as drug resistance.

Q: List the sites of drug biotransformation. What is the importance of understanding sites of…

A: Dentistry is a branch of medicine that focuses on teeth, gums, and mouth. etc. Dentistry is also…

Q: In your own words, explain why this procedure is referred to as an enzyme-linked immunosorbent…

A: ELISA is the most widely used test in serological diagnosis. It is well used for the detection of…

Q: Why is it important to measure the pharmacokinetics(PK) and metabolism of an antibody drug

A: Pharmacokinetics studies the changes of drug concentration in the body and the total amount of drug…

Q: DNA vaccines contain _______ DNA that stimulates cells to makeantigens.a. human, RNA b. microbial,…

A: DNA is the genetic material that carries genetic information in the form of coded nucleotide…

Q: Attenuated agents may induce immunity after a single dose may cause disease in immunocompromised…

A: Attenuated agents are live but weakened agents or pathogens

Q: What is drug delivery system? Briefly Explain the rational for developing modified release drug…

A: Any substance on consumption that causes a change in an organism's physiology or psychology is…

Immunology

Immunology is the division of science involved with the immune reactions occurring in living organisms. The organisms are accustomed to evolving internal defense mechanisms to evade the invasion of microbial pathogens. Diverse cells are connected with stimulating the immune responses, which produce inhospitable conditions to the microbes prompting their lysis and thus inhibits the multiplication of the pathogens. The immune system can distinguish the pathogens through the aid of cellular intercommunication and launch responses to destroy them.