Discuss how mutations in the 5’ splice site, 3’ splice site or branch point of an intron may disrupt RNA splicing and what the effect may be on the phenotype.

Biology (MindTap Course List)
11th Edition
ISBN:9781337392938
Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Chapter13: Gene Expression
Section13.5: Mutations
Problem 12LO: Give examples of the different classes of mutations that affect the base sequence of DNA in protein...
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Discuss how mutations in the 5’ splice site, 3’ splice site or branch point of an intron may
disrupt RNA splicing and what the effect may be on the phenotype.

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