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Q2.
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- 10. The enzyme that involved in the catalysis from alpha-ketoglutarate to glutamate is A. Alpha-ketoglutarate dehydrogenase B. Glutamate dehydrogenase C. Glutamate synthase D. Glutamate synthetase give explanation for both correct and incorrect options asapHi, help please. Discuss each method of regulating phosphofructokinase below as indicated by the circle. Discuss 1.) The type of regulation occurring, 2.) What compound or condition performs the regulation, 3.) How/why it influences the enzyme activity.10. Mention the Clinical Applications of Beta oxidation of fatty acids?
- Differences of Ketone Diet from being a supplemental factor for treatment?Discuss ketogenesis in details and also specify the ketone bodies.17. Which of the following is irrelevant in lipogenesis? a. acetyl-CoA b. acyl carrier protein (ACP) c. both a and b d. neither a nor b 18. Which chemical reaction is/are necessary in the elongation of fatty acids? a. hydrolysis b. dehydration c. both a and b d. neither a nor b 19. Which pathway is most likely activated when glycogen is depleted? a. B-oxidation b. lipogenesis c. both a and b d. neither a nor b
- 1. Select the INCORRECT statement about Glutamate dehydrogenase : a. Catalyzes the removal of NH4+ into glutamate b.Catalyzes the incorporation of NH*4 into a-ketoglutarate c. Catalyzes the removal of NH*4 from glutamate C d. Catalyzes the incorporation of NH'4 into a-keto acidThe “keto diet” is a dietary regimen in which carbohydrates are severely restricted, protein intake is low, and fat comprises 70–90% of daily calories. The diet causes “nutritional ketosis,” which is a different metabolic state than the ketosis that occurs in an untreated diabetic. The normal ketone body concentration is less than 0.6 mM. Explain why an individual on the keto diet may have a blood ketone body concentration of up to 3 mM. What biochemical pathways are active in an individual adhering to the keto diet? What pathways are largely inactive? Protein intake is kept low because a high-protein diet would inhibit ketosis. Explain why. Why might the keto diet lead to weight loss?Define the following terms:a. b-oxidationb. carnitinec. ketogenesisd. ketone bodiese. ketosis
- 1. Discuss fully the synthesis of triacylglycerol in the adipose tissue, muscles, intestines and liver. 2. Describe adequately the beta-oxidation of fatty acids. 3. Discuss the synthesis and utilization of ketone bodies.During fasting or starvation, the body converts to the production of ketone bodies. Diagram pathways utilized to produce ketone bodies and where they are used to create energy. Be sure to include which pathways are on and where. (20pts) Explain the role ketone bodies play in the liver, muscles, and the brain. Be sure to include the relationship of ketone bodies to carbohydrate metabolism. (20pts)Define a ketogenic diet and give an example of a ketogenic meal. Explain why ketone supplements would not be a useful alternative to the ketogenic diet as a cancer therapy. Why might dietary treatments be preferred over conventional treatment options?