Double-helical DNA has major and minor grooves because
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- Double-helical DNA has major and minor grooves because
A. DNA-binding proteins twist the DNA into a specific shave
B. The A:T and G:C basepairs have different dimensions
C. Purines, being larger, form the major groove while pyrimidines, being smaller, form the minor groove
D. The phosphoribose backbones of the two strands are not diametrically opposite
E.
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Solved in 3 steps
- Make the complementary strand for the following DNA template and label both strands as 5 to 3 or 3 to 5 (P = phosphate in the diagram). Draw an arrow showing the direction of synthesis of the new strand. How many hydrogen bonds are in this double strand of DNA? template: PAGGCTCGOH new strand:A circular double-stranded DNA molecule contains 4200 base pairs. Insolution, the molecule is in a B-form helix, with about 10.5 base pairsper turn. The DNA circle has 12 superhelical turns. What is its superhelixdensity s?For entertainment on a Friday night, a genetics professor proposed that his children diagram a polynucleotide strand of DNA. Having learned about DNA in preschool, his 5-year-old daughter was able to draw a polynucleotide strand, but she made a few mistakes. The daughter’sdiagram (represented here) contained at least 10 mistakes. Q. Make a list of all the mistakes in the structure of this DNA polynucleotide strand.
- For entertainment on a Friday night, a genetics professor proposed that his children diagram a polynucleotide strand of DNA. Having learned about DNA in preschool, his 5-year-old daughter was able to draw a polynucleotide strand, but she made a few mistakes. The daughter’sdiagram (represented here) contained at least 10 mistakes. Q. Draw the correct structure for the polynucleotide strand.When a double-stranded DNA molecule is exposed tohigh temperature, the two strands separate, and themolecule loses its helical form. We say the DNA hasbeen denatured. (Denaturation also occurs whenDNA is exposed to acid or alkaline solutions.)a. Regions of the DNA that contain many A–T basepairs are the first to become denatured as the temperature of a DNA solution is raised. Thinkingabout the chemical structure of the DNA molecule, why do you think the A–T-rich regionsdenature first?b. If the temperature is lowered, the original DNAstrands can reanneal, or renature. In addition to thefull double-stranded molecules, some molecules ofthe type shown here are seen when the moleculesare examined under the electron microscope. Howcan you explain these structures?If the sequence of bases in one strand of DNA is 5′ TAGCCT 3′,then the sequence of bases in the other strand isa. 3′ TCCGAT 5′.b. 3′ TAGCCT 5′.c. 3′ ATCGGA 5′.d. 3′ AACGGUA 5′.e. None of these are correct.
- Which of the following is true about the denaturation of double-helical DNA? A. Denaturation increases with decreasing temperature. B. Denaturation is accompanied by an increase in the absorption of UV light by DNA. C. G-C rich DNA melts at lower temperature than A-T rich DNA. D. Once denatured, DNA strands cannot anneal.The sequence of the DNA template strand is 3’– GACTTCC – 5’ What is the sequence of the DNA informational strand?Draw the full structure of the DNA strand: 5'-ATG-3' To the above strand, draw the complementary strand and illustrate the position of each hydrogen bond present between the nucleotides
- When DNA is heated sufficiently, the strands separate. The energy that it takes to separate the DNA is related to the amount of guanine and cytosine bases. Why is this so? (A) Adenine and thymine make 3 hydrogen bonds between each other, and guanine and cytosine don't make any hydrogen bonds. (B) Guanine and cytosine make 3 hydrogen bonds between each other, and adenine and thymine don't make any hydrogen bonds. (C) It takes more energy to break an A-T bond than it does a G-C bond. (D) It takes more energy to break a G-C bond than it does an A-T bond.One strand of a double-helical DNA has the sequence (5’)GCTCAATATTTCTCAAAAT ATTGCGC(3’). Write the base sequence of the complementary strand. What special type of sequence is contained in this DNA segment?Which of the following statements are true about doublestranded DNA?a. A + C = T + Gb. A + G = C + Tc. A + T = G + Cd. A/G = C/Te. A/G = T/Cf. (C + A) / (G + T) = 1
