Organic Chemistry: A Guided Inquiry
2nd Edition
ISBN:9780618974122
Author:Andrei Straumanis
Publisher:Andrei Straumanis
Chapter20: Acidity And Pka Of Phenols
Section: Chapter Questions
Problem 11E
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Step 1: Protection and deprotection in peptide synthesis
VIEWStep 2: Mechanism of deprotection - protonation
VIEWStep 3: Mechanism of deprotection - Loss of tertiary butyl carbocation
VIEWStep 4: Mechanism of deprotection - proton transfer
VIEWStep 5: Mechanism of deprotection - Decarboxylation
VIEWStep 6: Effect of physiological pH
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