Please help. Questions in images. SolventRf of ARf of BRf of C10% ethyl acetate-90% hexanes .12.07.0120% ethyl acetate-80% hexanes .34.29.1030% ethyl acetate-70% hexanes .53.42.2240% ethyl acetate-60% hexanes .72.61.35 The R; values determined on silica gel TLC plates for Compounds A, B, and C are tabulated inTable 11.5.(a) In order to purify Compound A, which of the solvent systems should be used to develop thecolumn in a flash chromatography procedure?(b) Could 90 mg of a mixture of Compound A and Compound B be separated by macroscaleflash column chromatography (10 mm column) using 20% ethyl acetate-80% hexanes as theeluting solvent?(c) Could 90 mg of a mixture of Compound A and Compound C be separated by macroscaleflash column chromatography (10 mm column) using 20% ethyl acetate-80% hexanes as theeluting solvent?

Chromatography is separation technique and it is used for separation of mixtures and the mixture…

Answered: ent Rf of A Rf of B Rf of C 10% ethyl…

ent Rf of A Rf of B Rf of C 10% ethyl acetate-90% hexanes .12 .07 .01 20% ethyl acetate-80% hexanes .34 .29 .10 30% ethyl acetate-70% hexanes .53 .42 .22

Fundamentals Of Analytical Chemistry

9th Edition

ISBN:9781285640686

Author:Skoog

Publisher:Skoog

Chapter33: High-performance Liquid Chromatography

Section: Chapter Questions

Problem 33.15QAP

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Please help. Questions in images.

Solvent	Rf of A	Rf of B	Rf of C
10% ethyl acetate-90% hexanes	.12	.07	.01
20% ethyl acetate-80% hexanes	.34	.29	.10
30% ethyl acetate-70% hexanes	.53	.42	.22
40% ethyl acetate-60% hexanes	.72	.61	.35

The R; values determined on silica gel TLC plates for Compounds A, B, and C are tabulated in
Table 11.5.
(a) In order to purify Compound A, which of the solvent systems should be used to develop the
column in a flash chromatography procedure?
(b) Could 90 mg of a mixture of Compound A and Compound B be separated by macroscale
flash column chromatography (10 mm column) using 20% ethyl acetate-80% hexanes as the
eluting solvent?
(c) Could 90 mg of a mixture of Compound A and Compound C be separated by macroscale
flash column chromatography (10 mm column) using 20% ethyl acetate-80% hexanes as the
eluting solvent?

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