Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter17: Metabolism: An Overview
Section: Chapter Questions
Problem 9P
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(c) Early researchers also investigated ER morphology by isolating
microsomal fractions
("rough ER vesicles"
from liver homogenates
and again viewing these fractions using
TEM (see image below). Explain how such an image matches to the 3D
reconstruction of the ER.
(b)
0.1 μm
Hint: What happens to the ER when
tissue/cells are "homogenised"?
Notice the scale bar compared to
that in the right image above.
Transcribed Image Text:(c) Early researchers also investigated ER morphology by isolating microsomal fractions ("rough ER vesicles" from liver homogenates and again viewing these fractions using TEM (see image below). Explain how such an image matches to the 3D reconstruction of the ER. (b) 0.1 μm Hint: What happens to the ER when tissue/cells are "homogenised"? Notice the scale bar compared to that in the right image above.
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