Examine the synthesis problem which converts 3-methylbutanoic acid to 2-bromo-1-chloro-3-methylbutane. Which of the following reaction sequenceswill yield the correct product?BrO 1. LIAIH, in dry ether followed by the addition of H,O2. Br2 + PBr3 followed by H2O3. PCI3 in etherO 1. PCI3 in ether2. Br2 + PBr3 followed by H2O3. LIAIH4 in dry ether followed by the addition of H20O 1. Br2 + PBR3 followed by H,O2. LIAIH, in dry ether followed by the addition of H203. PCI3 in etherO 1. Br2 + PBR3 followed by H202. PCI3 in ether3. LIAIH, in dry ether followed by the addition of H20

Alpha halogenation of carboxylic acid by using Br2/ PBr3 in H2O Reduction of carboxylic acid…

Answered: Examine the synthesis problem which…

Examine the synthesis problem which converts 3-methylbutanoic acid to 2- bromo-1-chloro-3-methylbutane. Which of the following reaction sequences will yield the correct product?

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter16: Aldehydes And Ketones

Section: Chapter Questions

Problem 16.63P

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Question

Examine the synthesis problem which converts 3-methylbutanoic acid to 2-
bromo-1-chloro-3-methylbutane. Which of the following reaction sequences
will yield the correct product?
Br
O 1. LIAIH, in dry ether followed by the addition of H,O
2. Br2 + PBr3 followed by H2O
3. PCI3 in ether
O 1. PCI3 in ether
2. Br2 + PBr3 followed by H2O
3. LIAIH4 in dry ether followed by the addition of H20
O 1. Br2 + PBR3 followed by H,O
2. LIAIH, in dry ether followed by the addition of H20
3. PCI3 in ether
O 1. Br2 + PBR3 followed by H20
2. PCI3 in ether
3. LIAIH, in dry ether followed by the addition of H20

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