Answered: Explain the difference in the pKa…

Science

Chemistry

Explain the difference in the pKa values of the carboxyl groups of alanine, serine, and cysteine.

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter26: Biomolecules: Amino Acids, Peptides, And Proteins

Section26.SE: Something Extra

Problem 20VC

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Concept explainers

Organometallic compounds of d-block elements

The transition metals can form complexes since they have vacant d orbitals. They are also termed Coordination compounds. The organometallic compounds of the transition metals could be used as catalysts as well as reagents. For example, organocadmium, organozinc, organocopper, Grignard are used as the reagents for several reactions. Most of the complexes of organo transition metals are used as catalysts for many organic transformation reactions.

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Explain the difference in the pK_a values of the carboxyl groups of alanine, serine, and cysteine.

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Explain why the pI of lysine is the average of the pKa values of its two protonated amino groups.
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Taking the structure of the amino acids into account, give a comparative discussion of these pK values : Alanine : 2.34 : 6.1 : 9.70 Histidine: 1.82 : 9.17
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