Nucleotides
It is an organic molecule made up of three basic components- a nitrogenous base, phosphate,and pentose sugar. The nucleotides are important for metabolic reactions andthe formation of DNA (deoxyribonucleic acid) and RNA (ribonucleic acid).
Nucleic Acids
Nucleic acids are essential biomolecules present in prokaryotic and eukaryotic cells and viruses. They carry the genetic information for the synthesis of proteins and cellular replication. The nucleic acids are of two types: deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). The structure of all proteins and ultimately every biomolecule and cellular component is a product of information encoded in the sequence of nucleic acids. Parts of a DNA molecule containing the information needed to synthesize a protein or an RNA are genes. Nucleic acids can store and transmit genetic information from one generation to the next, fundamental to any life form.
Explain the Structures of activators?
Activator;- are modular proteins contains a single DNA binding domain and one are few activation domains.The different domains are linked through polypeptide regions... DNA binding domains in eukaryotic transcription factors exhibit a variety of structures...
structures of activators:-
catabolite activator protein;-CAP also known as cAMP receptor proteins activates transcription at the lac operon of the bacterium Ecoli. cAMP produced during glucose starvation ,binds to CAP, causes conformational cahnge that allows CAP to bind to a DNA sites site located adjacent to the lac promoter.CAP then makes a direct protein-protein interaction with RNA polymerase that recruits RNA polymerase to the lac promotor.
5' __lacl___CAP -P- O- ___lacZ_ ___lacY____ __lacA__ ________3' binding site
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