Explain why a methoxy group (CH3O) increases the rate of electrophilic aromatic substitution, but decreases the rate of nucleophilic aromatic substitution.

Q: Which bases can be used for an E2 reaction that follows Hofmann's rule? Choose all that apply. O…

A: According to Hoffman rule, an elimination reaction occurs to produce less substituted alkene which…

Q: Br is a better nucleophile than HSO4

A: Nucleophilic substitution reaction is the reaction in which one nucleophile substitutes the other…

Q: Choose all the nucleophiles OH-     H3O+     NH4+     CH3OH     (CH3)3CLi     CH3CH2CH3     NaNH2…

A: Nucleophile :-A chemical species which have free pair of electronsor can denote pair of electrons…

Q: (с) I or II CH3 CH3 (d) H3C CH3 I or II :0: :0:

A:

Q: Acid Halide Preparation reaction mechanism: Please use HCl and SOCl2 as reagents

A: Formation of acid halide using HCl and SOCl2 as reagent:

Q: How does the strength of the nucleophile affect an SN1 or SN2 mechanism?

A: Given reaction types,     SN1 reaction mechanism     SN2 reaction mechanism

Q: Which reacts faster in an E1 reaction?

A: A weak base is favoured E1 reaction because carbonation is the intermediate in that reaction which…

Q: Show how this cyclic ether compound could be prepared from an alkyl halide compound in an SN2…

A:

Q: What is the major product of this reaction sequence?

A: Correct option is (b) i.e pentanoicacid acid is the final product.

Q: Give one example of Williamson ether synthesis. Show the reactants materials and the product. Draw…

A: As per the multiple-question rule- I am answering the first question asked (Williamson-ether…

Q: What is the appropriate electrophile nucleophile and solvent to achieve this final product

A:

Q: This reaction is an example of conjugate addition of a nucleophile to an a,ß-unsaturated carbonyl.…

A: The two resonance structures of the enolate anion intermediate for this reaction can be drawn as…

Q: Explain the strength of the base usually determines whether a reaction follows the E1 or E2…

A: Elimination reaction is the reaction in which small molecule like water, ammonia are eliminated.…

Q: List A-D in order of increasing ability of a nucleophile to displace a leaving group in a…

A: a) & b)  Aqueous acetone is a protic solvent (the water H-bonds tightly to F-) so iodide will…

Q: Drawing the Products of an SN1 Reaction Label the nucleophile and leaving group, and draw the…

A: the nucleophile and leaving group

Q: Why does increasing alkyl substitution increase the rate of an E2 reaction?

A: The increase in E2 reaction rate with increasing alkyl substitution can be rationalized in terms of…

Q: Why does bromination give exclusively anti products while chlorination gives a mixture of syn and…

A: Halogenation is the addition of halogens to alkenes. Halogenation usually gives anti products. If…

Q: Which of the following conditions manifest the Markovnikov rule? When the electrophile attaches to…

A:

Q: Which of the following could act as a nucleophile?

A: Given:To give which of the following could act as a nucleophile

Q: Show how you might synthesize this compound from an alkyl bromide and a nucleophile in an SN2…

A: This reaction is carried out in polar aprotic solvent like DMSO

Q: Explain why the following alkyl halide does not undergo a substitution reaction, regardless of the…

A: The Following alkyl halide does not undergo a substitution reaction, regardless of the base because-…

Q: Explain Electrostatic potential maps of four halomethanes (CH3X)

A: The given reaction is nucleophilic substituion reaction in which nucleophile substitute the halogen…

Q: Br NH2 NANH2 NaBr

A: The reaction of bromobenzene with sodium amide results in the generation of aniline and sodium…

Q: In electrophilic aromatic substitution, a group attached to the aromatic ring does not affect ring…

A: In electrophilic aromatic substitution, a group attached to the aromatic ring does not affect ring…

Q: ?Which of the following is not a nucleophile اخترأحد الخيارات a. CH30CH3 b. NH3 C. FeBr3

A: To determine which of the following is not a nucleophile. CH3OCH3 NH3 FeBr3 Br-

Q: Question attached

A: E1 reaction is unimolecular reaction, where one substituent is removed from the molecule. In a E1…

Q: Which types of halide will react faster in an SN1 reaction?

A:

Q: Identify the stronger nucleophile in each pair of anions.a. Br- or Cl- in a polar protic solventb.…

A: a.Polar protic solvents contain hydrogen atoms bonded to electronegative atoms namely O or N.The…

Q: Circle the compound that has the least nucleophilic aromatic ring. phenol bromobenzene toluene…

A: A question based on the nucleophilic nature of aromatic rings, which is to be accomplished.

Q: a. Strong bases are [ Select ] nucleophiles. b. Electron-withdrawing groups nearby a nucleophilic…

A: Bases try to abstract hydrogen whereas nucleophiles attack electron deficit carbon atoms. The groups…

Q: Rank the relative reactivity of nucleophiles. The shortest time means fastest reaction, which gets…

A: To arrange the nucleophile in order of reactivity.,

Q: In the E1 reaction, how is the rate affected when the concentration of attacking nucleophile is…

A: Elimination reaction-is type of organic reaction in which two substituents are removed from molecule…

Q: Which of the following is a weak nucleophile? OH-       H2O       CH3O-

A: We have to predict weak nucleophile .

Q: an SN2/SN1 reaction occur

A: We know that the weaker base is a good leaving group. While strong base are poor leaving group.…

Q: Rank the reactivity of the following compounds according to the SN2 reaction? Please explain why a)…

A: The SN2 reaction mechanism involves the nucleophilic substitution reaction of the leaving group…

Q: Explain why alkylation of an a-carbon works best if the alkyl halide used in the reaction is a…

A: The alkylation reaction of an α-carbon depends on the R-X (alkyl halide) used in the reaction. The…

Q: For each pair of molecules click on the one which will undergo an E2 reaction more rapidly when…

A: From given  Elimination reaction of E2 is briefly described and each pair is compared accordingly as…

Q: OH но OH BF3'Et20 HO HO `OH

A: Alcohol react with lewis acid and carbon attached to -OH becomes more electrophillic which further…

Q: explain why a polar aprotic solvent speeds the rate of an SN2 mechanism

A: A polar aprotic solvent is a solvent that lacks an acidic proton and is polar.  Polar aprotic…

Q: What will happen if a carboxylic acid reacts with a Grignard reagent? Draw and explain the…

A: The mechanism is as follows:

Q: Addition of excess acid halide to an alkyne would produce a/an ___ dihalide Vicinal       Geminal…

A: Addition of excess acid halide to an alkyne would produce a/an ___ dihalide .. answer is given…

Q: The SN2 reaction shows a reversible mechanism when the basic strength nucleophile and leaving group…

A: Generally SN2 reactions are substitution nucleophilic biomolecular reactions. The mechanism involves…

Q: This reaction is an example of conjugate addition of a nucleophile to an a,ß-unsaturated carbonyl.…

A: The alpha hydrogen to the carbonyl group is acidic in nature and this hydrogen is removed in…

Q: Like acid chlorides, acid anhydrides react with alcohols in the presence of pyridine to form esters.…

A: Electrophile is electron deficient species whereas Nucleophile is electron rich species

Q: Which of the following alkyl halides is most likely to undergo rearrangement by a methyl shift in an…

A:

Q: a-Determine if it will follow an Sn1 or SN2 mechanism and state which it will follow. b-Explain the…

A: The question is based on the concept of organic reaction mechanism . We have to identify the product…