Explain why alkylation of an α-carbon works best if the alkyl halide used in the reaction is a primary alkyl halide, and why alkylation does not work at all if a tertiary alkyl halide is used.

Q: reagents in the correct order for the synthesis of the target molecule?

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Q: a) b) HO, HO c) OH Br

A: The cyclohexanecarbaldehyde will firstly reduce to alcohol via a reducing agent. The reducing agent…

Q: (b) Why is the Claisen-Schmidt reaction a special type of aldol condensation?     one of the…

A: Answers of the above questions given below.

Q: Provide a mechanistic explanation (using curly arrows) for the observed mixture of products in the…

A: Dehydration of alcohols Dehydration is the process of removal of water. It is done using acids, that…

Q: A different way of synthesising the product 4,4- diphenylbut-3-en-2-one is via an aldol…

A: aldol condensation is a condensation reaction  in which an  enolate ion reacts with a carbonyl…

Q: Using lithium enolate with ester and alkyl halide, draw the reactants and steps of the reaction that…

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Q: How does a protic solvent make strong bases less nucleophilic?

A: How does a protic solvent make strong bases less nucleophilic has to be given.

Q: Draw the product for the following reaction.

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Q: Draw the product of the following reaction

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Q: 10.Draw the structure of the product of the reagent(s) with the substrate: SOCI,

A: We’ll answer the first question since the exact one wasn’t specified. Please submit a new question…

Q: what is the difference of the products in an E2 vs E1 reaction?

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Q: What steps use in the Robinson Annulation?

A: Robinson Annulation is an organic reaction, in which the reaction between methyl vinyl ketones and…

Q: Show the product of treating this anhydride with   reagent

A: Given: Treatment of given anhydride with methanol

Q: Which routes could be used to synthetize the product in the center?

A: We have given the product in the center which is an organic compound names as alchol. We have given…

Q: ОН О OH ОН О H. B For the "crossed" aldol reaction that lead to product C, did the kind of base used…

A: The structure of product C is represented as follows:

Q: meta-directing group will place the electrophile into a 1,2- or 1,4-relationship with the dirscting…

A: A meta-directing group will place the electrophile into a 1,2- or 1,4-relationship with the…

Q: Draw the product of the reaction of the following compound with a base:

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Q: If the nucleophile in a condensation reaction is an enolate derived from an ester, what type(s) of…

A: Here the nucleophile involved in the condensation reaction is an Enolate derived from an ester which…

Q: TRUE or FALSE. When phenol undergoes an FC alkylation with methyl chloride and aluminum chloride,…

A: We have to predict whether given Statement is correct or not.

Q: For each pair, predict the stronger nucleophile in the SN2 reaction (using an alcohol asthe…

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Q: Draw the product for the following reaction

A: Solution

Q: alkenes possessing five carbons or fewer. OEt ethyl acetoacetate or EtO OEt diethyl malonate and…

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Q: Which pathway is favored for the reaction of N2OCH3 with 1-bromonane? NaOCH3 Br A. SN1 B. SN2 С. Е2…

A: The reaction between 1-bromononane and NaOCH3 occurs as:

Q: 6 Show how to synthetize the following target: (a)

A: Organic reaction mechanisms.

Q: Write the complete mechanism for the hydroxide ion catalyze reaction of cyclohexanone and…

A: Hydroxide ion (OH-) act as a catalyst which can abstract the acidic alpha proton to form the enolate…

Q: Draw the product of the following reaction.

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Q: Draw the two ethyl esters which could be used to make the mixed Claisen product shown below.

A: Clasien ester condensation :  The Claisen condensation is a carbon–carbon bond forming reaction that…

Q: Draw the product of the following reaction:

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Q: Draw the structures of 2 anionic groups that are not considered good leaving groups in an SN2…

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Q: Provide the reagents (up to 3 steps) for the following reaction. (The acetal cannot be formed) HO

A: When ketone react with alcohol in limited amount hemiacetal formed.

Q: Choose the best substrate for a substitution reaction. O Alkyl iodide O Alkyl bromide O Alkyl…

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Q: Please draw the synthesis of 6-dimethylheptane from an alkyne and an alkyl halide.

A: We have to draw the synthesis of 6-dimethylheptane from an alkyne and an alkyl halide.

Q: 1. What is name of the starting material for the reaction sequence shown in the box? CH3 NaOH, H20…

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Q: What is the Aldol addition product formed from reaction of PHCH2CHO with itself?

A: Given :- PhCH2CHO + PhCH2CHO + base → To determine :- product obtained in above aldol addition…

Q: In an aldol condensation reaction, what is the difference if we use an ethanolic or aqueous NaOH…

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Q: Draw the products of the two step reaction sequence shown below. Ignore inorganic byproducts. If the…

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Q: What type of aldehydes undergo Aldol condensation?

A: Interpretation: Type of aldehydes undergo Aldol condensation.

Q: Draw the product of this Robinson annulation reaction. Ignore inorganic byproducts. KOH, CH3CH2OH…

A: In Robinson annulation first of all Michael addition reaction occur then Aldol condensation occur.

Q: In a mixed aldol condensation with unknown aldehydes and ketones reaction what type of isomers can…

A: By analysing geometry of aldol products after E1CB elimination reaction.

Q: Show two different ways to make an epoxide from a trans alkene, one that gives the trans epoxide and…

A: Trans product :

Q: Draw the reaction mechanism of the elimination reaction of 2 bromobutane with a hydroxide ion acting…

A: Elimination reaction : An elimination reaction is a type of chemical reaction in which several atoms…

Q: Which compound is a major product of the reaction sequence shown in the box? 1. EtO Na+ OEt 2. HСI,…

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Q: Explain why alkylation of an a-carbon works best if the alkyl halide used in the reaction is a…

A: The alkylation reaction of an α-carbon depends on the R-X (alkyl halide) used in the reaction. The…

Q: Explain why hydroxide ion catalyzes the reaction of piperidine with 2,4-dinitroanisole but has no…

A: The mechanism of the reaction taking place between piperidine and 2,4- dinitroanisole is as follows:

Q: What are the conditions needed in a synthesis to promote an SN1 type of reaction? For example do we…

A: SN1 reaction is a nucleophilic substitution reaction in which the rate determining step depends on…

Q: Give any two conditions where enol tautomer is more stable than keto tautomer

A: Any two conditions where enol tautomer is more stable than keto tautomer has to be given.

Q: Propose a synthesis of the following target compound starting from benzonitrile. Remember to start…

A: Benzonitrile is first fluorinated then reduced to give benzyl amine which was then alkylated.

Q: Select reactants and reagents that can be used in a crossed Aldol Condensation to make the following…

A: Since you have asked multiple questions, we will solve the first question for you. If you want any…

Q: Explain why a diazonium group on a benzene ring cannot be used to direct an incoming substituent to…

A: Generally, the electron withdrawing substituent present in benzene ring can direct an incoming…