fetal and Studies of oxygen transport in pregnant mammals show that the O2-saturation curves maternal blood are markedly different when measured under the same conditions. Fetal erythrocytes contain a structural variant of hemoglobin, HbF, consisting of two a and two y (a2 y2), whereas maternal erythrocytes contains HbA (a2 B2). 1. 1.0 HbF +BPG 0.5 E HbA +BPG 2 4 8 10 pO2 (kPa) a. Which hemoglobin has a higher affinity for oxygen under physiological conditions, HbA or HbF? Explain. b. What is the physiological significance of the different O2 affinities?

Appl Of Ms Excel In Analytical Chemistry
2nd Edition
ISBN:9781285686691
Author:Crouch
Publisher:Crouch
Chapter3: Statistical Tests With Excel
Section: Chapter Questions
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fetal and
Studies of oxygen transport in pregnant mammals show that the O2-saturation curves
maternal blood are markedly different when measured under the same conditions. Fetal erythrocytes
contain a structural variant of hemoglobin, HbF, consisting of two a and two y (a2 y2), whereas
maternal erythrocytes contains HbA (a2 B2).
1.
1.0
HbF
+BPG
0.5 E
HbA
+BPG
2
4
8
10
pO2 (kPa)
a. Which hemoglobin has a higher affinity for oxygen under physiological conditions, HbA or HbF?
Explain.
b. What is the physiological significance of the different O2 affinities?
Transcribed Image Text:fetal and Studies of oxygen transport in pregnant mammals show that the O2-saturation curves maternal blood are markedly different when measured under the same conditions. Fetal erythrocytes contain a structural variant of hemoglobin, HbF, consisting of two a and two y (a2 y2), whereas maternal erythrocytes contains HbA (a2 B2). 1. 1.0 HbF +BPG 0.5 E HbA +BPG 2 4 8 10 pO2 (kPa) a. Which hemoglobin has a higher affinity for oxygen under physiological conditions, HbA or HbF? Explain. b. What is the physiological significance of the different O2 affinities?
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