Which of the following describes forward genetics? Utilizing consensus regions within a genome to hypothesize the location of genes. Beginning with a phenotype and determining the genetic basis responsible for it. Performing sequence comparison between normal and diseased samples to identify genetic alterations specific to each sample type. Beginning with a gene and determining the phenotypic impact of mutating it. To move from the 5' to the 3'direction within a chromosomal sequence in order to systematically characterize the structure of the genome.

Which of the following describes forward genetics? Utilizing consensus regions within a genome to hypothesize the location of genes. Beginning with a phenotype and determining the genetic basis responsible for it. Performing sequence comparison between normal and diseased samples to identify genetic alterations specific to each sample type. Beginning with a gene and determining the phenotypic impact of mutating it. To move from the 5' to the 3'direction within a chromosomal sequence in order to systematically characterize the structure of the genome.

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter15: Genomes And Genomics

Section: Chapter Questions

Problem 7QP: Which of the following is NOT an activity carried out in the field of bioinformatics? a. collecting...

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Which of the following most accurately describes the process of DNA cloning? set of laboratory procedures that consist of cutting a segment of DNA with restriction enzymes set of laboratory procedures that uses living cells to mass-produce specific DNA fragments set of laboratory procedures by which a DNA fragment is transferred from a living organism to a SNP chip the manipulation of DNA fragments in a laboratory using modern techniques of molecular biology set of laboratory procedures that consist of isolating of a DNA fragment from a living organism and inserting it into a plasmid
Which of the following best describes the process of DNA sequencing? a. DNA is separated on a gel, and the different bands are labeled with fluorescent nucleotides and scanned with a laser. b. A laser is used to fluorescently label the nucleotides present within the DNA, the DNA is run on a gel, and then the DNA is broken into fragments. c. Nucleotides are scanned with a laser and incorporated into the DNA that has been separated on a gel, and then the DNA is amplified with PCR. d. Fragments of DNA are produced in a reaction that labels them with any of four different fluorescent dyes, and the fragments then are run on a gel and scanned with a laser. e. DNA is broken down into its constituent nucleotides, and the nucleotides are then run on a gel and purified with a laser.
Which of the following is NOT an activity carried out in the field of bioinformatics? a. collecting and storing DNA sequence information produced by various genome sequencing projects b. analyzing genome sequences to determine the location of genes c. determining the three-dimensional structure of proteins d. comparing genomes of different species e. none of these
Bioinformatics is the science of using computational methods (specialized software) to decipher the biological meaning of information contained within organismal system. Comparisons of experimental data involving DNA sequences generated by different laboratories are critically dependent on the use of a universally agreed-upon standard of analysis. Which of the following is universally used as the agreed-upon standard of analysis for these comparisons? Group of answer choices A GenBank database. A species reference sequence (RefSeq) system. A genomic library collection. A ChIP/chip analysis system.
The human genome has been fully mapped by the Human Genome Project. Information on the human genome is now freely available on DNA databases. Which statement best describes an ethical issue concerning the Human Genome Project? Responses The money invested in this project can be utilized for other research. The money invested in this project can be utilized for other research. The complete information about the human genome can be utilized to map human ancestry. The complete information about the human genome can be utilized to map human ancestry. The complete information about the human genome can lead to devastating consequences on Earth’s biodiversity. The complete information about the human genome can lead to devastating consequences on Earth’s biodiversity. The human genome will provide information about inherited diseases, which raises the possibility of genetic manipulation in individuals.
Being able to understand the relationship between DNA, mRNA, tRNA, ribosomes and proteins, is necessary for any researcher interested in gene therapy. Gene therapy is dedicated to correcting genetic defects by replacing mutated genes with wildtype versions. This can include complete removal and introduction of a working copy of the entire gene (using knock-outs and knock-ins) or removal of only the actual mutated nucleotide. Sickle Cell Disease is an example of a recessive disorder based on a single-point mutation: GAG becomes GTG, which encodes a new amino acid. One would only need to replace a single base to correct the disorder making it very attractive to gene therapy researchers. The mutant sickle cell allele is called HbS (for sickled hemoglobin) while the wt allele is HbA. Pretend that Arcel Kasongo, a masters student from Cambridge, is studying for an oral exam on gene therapy, and has an especial interest in the disorder since he comes from the Democratic Republic of Congo…
Being able to understand the relationship between DNA, mRNA, tRNA, ribosomes and proteins, is necessary for any researcher interested in gene therapy. Gene therapy is dedicated to correcting genetic defects by replacing mutated genes with wildtype versions. This can include complete removal and introduction of a working copy of the entire gene (using knock-outs and knock-ins) or removal of only the actual mutated nucleotide. Sickle Cell Disease is an example of a recessive disorder based on a single-point mutation: GAG becomes GTG, which encodes a new amino acid. One would only need to replace a single base to correct the disorder making it very attractive to gene therapy researchers. The mutant sickle cell allele is called HbS (for sickled hemoglobin) while the wt allele is HbA. Pretend that Arcel Kasongo, a masters student from Cambridge, is studying for an oral exam on gene therapy, and has an especial interest in the disorder since he comes from the Democratic Republic of Congo…
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Give the scope of the following fields in Applied Genetics: Metagenics Genetic Engineering Phylogenetics