For problem 8.17, all of the reactions will be SN2. For each reaction, identify and evaluate each nucleophile (strong? weak? Strong or weak as a base?) Also, evaluate each solvent as polar protic or polar aprotic. I recommend drawing the structure of each solvent. (g) Sodium methanethiolate (NaSCH3) in ethanol

For problem 8.17, all of the reactions will be SN2. For each reaction, identify and evaluate each nucleophile (strong? weak? Strong or weak as a base?) Also, evaluate each solvent as polar protic or polar aprotic. I recommend drawing the structure of each solvent. (g) Sodium methanethiolate (NaSCH3) in ethanol

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter14: Elimination

Section: Chapter Questions

Problem 24E

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Similar questions

When drawing organic chemistry mechanisms with NaOCH3, do we automatically dissociate it into Na+ and OCH3-, making it easier to go through SN2 and/or E2 reactions? Does NaOCH3 dissociate, and is this why it is a strong nucleophile?
Fill in the blank for this reaction by using the E1 mechanism that includes rearrangemnt
12c. If you could, please provide an explaination for why the major product would be the SN2 product rather than E2 product?
a. What are the products of following reactions?b. Write the reaction mechanism for each using the right arrows and define it as Sn2, Sn1, E2 or E1.c. Explain why do you choose that product and mechanism or in case something else happens explain why.
In which case is it correctly given which reagents should be above the arrows in the reaction given below?
Working Backwards Parte Deux. a.First, identify which functional groups changed during the reaction. Did stereochemistry change too? b. Based on your answers to A and B, what kind of reaction occurred here, SN1 or SN2? c.Suggest reagents and solvent that could accomplish this reaction.
Rank these in order of increasing reactivity in an SN1 reaction
1. Draw a reasonable arrow-pushing mechanism for the transformation shown along. 2. Identify nucleophiles and electrophiles 3. Name any type of reactions taking place like E2 or E1 4. Account for any regio- or stereoselectivity
While dehydrating 2-Methlycyclohexanol to 1-Methlycyclohexanol, and 3-Methlycyclohexanol 1)what is the common problem associate with E1 reaction? Discuss the intermediate. 2) Briefly compare and contrast E1 vs E2 Elimination reactions. INclude details such as speed of the reactions in relation to each other, rate-determining steps (E1), and stereochemical requirements (E2). Mention whether the steps of the reactions are reversible and discuss the conditions that can drive the equilibrium to favor product formation.
How does increasing base, solvent, or alkyl halide or aptly halide + base affect or decreasing them affect the reaction rate for e2/e1 and sn2/sn1? Please provide examples
For SN1 Explain the order in which 2o (secondary) alkyl halides reacted (fastest to slowest) and explain why. 2o (secondary) compounds listed are: (see picture) 2-chlorobutane 2-bromobutane bromobenzene bromocyclopentane bromocyclohexane Base your explanations on the following considerations: the nature of leaving group, the effect of structure, steric hindrance and any other feature. Be sure to explain which alkyl halides did not react and why
1. Which of the following is the strongest nucleophile? Refer to the diagram below with an MeOH, MeSH, etc. 2. Which of the following is true about the stereochemistry of SN1 reaction?a.retention of configuration at the electrophilic centerb.50:50 mixture of retention and inversion of configuration at the electrophilic centerc.inversion of configuration at the electrophilic centerd. slightly more inversion than retention at the electrophilic center