For the following question, please explain in as much detail as possible. Below is a human pedigree and corresponding RFLP data. Explain the type of transmission for the type of albinism depicted in this family. What does the pedigree tell you about the individual labeled Y's genotype? There are two genes known to cause this type of albinism found in this family: OCA1 and OCA2. If we know 11 (albino great grandmother) had mutation in OCA1 which gene would you hypothesize is mutated in individual Y's genome? Explain your reasoning. generations Key: D ở abino 1ỏ bỏ bỏ ởóbb IV 2 IV3 IV5 IV6 IV 15 IV16 | IV17 (Y) Ped. III2 III3 IVi IV4 III13 III14 (P) (Q) (X) ID Band size 20kb 15kb 12kb 10kb 8kb 5kb 3kb X X X X X 2kb

For the following question, please explain in as much detail as possible. Below is a human pedigree and corresponding RFLP data. Explain the type of transmission for the type of albinism depicted in this family. What does the pedigree tell you about the individual labeled Y's genotype? There are two genes known to cause this type of albinism found in this family: OCA1 and OCA2. If we know 11 (albino great grandmother) had mutation in OCA1 which gene would you hypothesize is mutated in individual Y's genome? Explain your reasoning. generations Key: D ở abino 1ỏ bỏ bỏ ởóbb IV 2 IV3 IV5 IV6 IV 15 IV16 | IV17 (Y) Ped. III2 III3 IVi IV4 III13 III14 (P) (Q) (X) ID Band size 20kb 15kb 12kb 10kb 8kb 5kb 3kb X X X X X 2kb

Name: For the following question, please explain in as much detail as possi
Uploaded: 2024-03-20T06:43:04.000Z
Channel: Bartleby
Description: For the following question, please explain in as much detail as possible.Below is a human pedigree and corresponding RFLP data. Explain the type of transmission for the type ofalbinism depicted in this family. What does the pedigree tell you about t

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter4: Pedigree Analysis In Human Genetics

Section: Chapter Questions

Problem 3QP: Pedigree Analysis Is a Basic Method in Human Genetics Using the pedigree provided, answer the...

See similar textbooks

Similar questions

Given the karyotype shown at right, is this a male or a female? Normal or abnormal? What would the phenotype of this individual be?
The young woman shown at right has albinismvery pale skin, white hair, and pale blue eyes. This phenotype is due to the absence of melanin, which imparts color to the skin, hair, and eyes. It typically is caused by a recessive allele. In the following situations, what are the probable genotypes of the father, the mother, and their children? a. Both parents have normal phenotypes; some of their children are albino and others are not. b. Both parents and all their children are albino. c. The mother is not albino, the father is albino, and one of their four children is albino.
The gene controlling ABO blood type and the gene underlying nail-patella syndrome are said to show linkage. What does that mean in terms of their relative locations in the genome? What does it mean in terms of how the two traits are inherited with respect to each other?
A pedigree analysis was performed on the family of a man with schizophrenia. Based on the known concordance statistics, would his MZ twin be at high risk for the disease? Would the twins risk decrease if he were raised in an environment different from that of his schizophrenic brother?
Pedigree Analysis Is a Basic Method in Human Genetics Using the pedigree provided, answer the following questions. a. Is the proband male or female? b. Is the grandfather of the proband affected? c. How many siblings does the proband have, and where is he or she in the birth order?
Below is a pedigree chart for a family that has a history of Alkaptonuria. Individuals infected with this condition can have darkened skin, brown urine, and can suffer from joint damage and other complications. Given this pedigree answer the following questions. Given the data in the pedigree chart is this genetic condition autosomal dominant or autosomal recessive? What are the genotypes for #1, #2, and #3? If either of the 4th generation "aa" females were to mate with a homozygous dominant male would any of their offspring illustrate the phenotype? Why or why not?
The genotype of EB27 and EB67 are unknown. Based on pedigree, what are the most likely genotype of each individual?
The pedigree below shows a family affected by a disease. Assume that the individuals marked with an asterisk (*) do not carry any allele associated with the affected phenotype, no other mutation spontaneously occurred, and complete penetrance. Answer the following questions below. Use the notation XR for the allele associated with the dominant phenotype and Xr for the allele associated with the recessive phenotype. Q1) Give the genotypes for as many individuals in the pedigree as possible.
The Mic2 gene in humans is present on both the X and Y chromosome. Let’s suppose the Mic2 gene exists in a dominant Mic2 allele, which results in normal surface antigen production, and arecessive mic2 allele, which results in defective surface antigenproduction. Using molecular techniques, it is possible to distinguish homozygous and heterozygous individuals. By followingthe transmission of the Mic2 and mic2 alleles in a large human pedigree, would it be possible to distinguish between pseudoautosomalinheritance and autosomal inheritance? Explain your answer
Over a thousand different alleles at the CFTR locus have been discovered that can cause cystic fibrosis. What difficulties might the presence of so many different alleles at this locus create for the diagnosis and treatment of cystic fibrosis?
A RFLP is discovered that is linked to the gene for Duchenne’s muscular dystrophy (DMD). DMD is an X-linked, recessive trait. The RFLP is 2 map units from the gene for DMD. Consider the following pedigree and Southern blot using a probe that hybridizes to the RFLP. Which band/s is/are associated with DMD? What is the genotype for individuals 3 and 4? (Remember, this is an X linked disease, so use X’s and Y’s to denote). Individual 9 married a man who does NOT have muscular dystrophy, and she is pregnant. DMD is an X-linked trait. What is the probability for their child to have DMD? An amniocentesis is performed and it is determined that 9’s child in utero has only a 10 kb band that hybridizes to the same probe used above. What can you say about the child now?
What will be the results of the following crosses, where N is black, n is brown, L is short hair and l is long hair. Make the tables and the corresponding explanation: 1. Crossing a Nnll woman dog with a Nnll dog. 2. Crossing a NnLl woman dog with a NnLl dog 3. Crossing a woman dog nnLl with a dog NNll