Galactosemia is a rare autosomal recessive disease that causes mental retardation. Individuals with galactosemia never reproduce. In a large human population the frequency of individuals with galactosemia is 1 in 118 000. Calculate the rate of mutation to the galactosemia allele, assuming mutation-selection equilibrium in the population.

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
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Author:Michael Cummings
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Chapter10: From Proteins To Phenotypes
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Galactosemia is a rare autosomal recessive disease that causes mental retardation.
Individuals with galactosemia never reproduce. In a large human population the
frequency of individuals with galactosemia is 1 in 118 000, Calculate the rate of mutation
to the galactosemia allele, assuming mutation-selection equilibrium in the population.
Transcribed Image Text:Galactosemia is a rare autosomal recessive disease that causes mental retardation. Individuals with galactosemia never reproduce. In a large human population the frequency of individuals with galactosemia is 1 in 118 000, Calculate the rate of mutation to the galactosemia allele, assuming mutation-selection equilibrium in the population.
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