Generally speaking, there are four types of mutations. Which of two of these four have the main effects on fitness? beneficial O deleterious O lethal neutral
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- Point mutations arise more commonly than other types of mutations. -True or FalseWith regard to mutations, what is meant by the terms“harmful,” “beneficial,” and “neutral”? Why it issometimes an oversimplification to consider a mutation aseither harmful, beneficial, or neutral?Which of the following terms refer to the case when a mutation results in a significant decrease or a complete loss of the functional activity of a gene product? a. gain-of-function mutation b. loss-of-function mutation
- What are the three possible effects on the cell (or organism) when a mutation occurs in DNA? Which ones are most common? Which one is rare?Compare benefi cial and detrimental eff ects of mutations.Define the following terms:a. point mutationb. transition mutationc. transversion mutationd. silent mutatione. missense mutation
- Explain the difference between a gain-of-functionmutation and a dominant-negative mutation. Why areboth these types of mutation usually dominant?Which of these outcomes is most likely to result in a leaky mutation?What types of mutations occur (i.e. describe base substitution vs. frameshift, silent, missense, and nonsense mutations)?
- Which of the following mutations is NOT a point mutation? A. Missense mutation B. Insertion mutation C. Nonsense mutation D. Silent mutationDescribe the primary causes, types, and outcomes of mutations.Give an example of a mutation that is beneficial and one that islethal or harmful.Describe the primary causes and types of mutations. Give an example of a mutation that is benefi cial and one that is lethal or harmful.