Given an observed F2 data set, a specified gene, and two phenotype classes (disease and wild type), the number of degrees of freedom for the chi-square goodness of fit test when studying the F2 generation is:
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Given an observed F2 data set, a specified gene, and two
A)-1.
B)0.
C)2.
D)1.
E)3.
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- What is the benefit of doing a modified Furter-Meyer Test? What is the premise of this experiment? How would you know if this test yielded a positive result?what does the data table in Griffith's experiment represents?What are the inferences from Griffith's table? What are type 1, 2 and 3. R and S strains?What is the first variable that can be calculated given these data, and what is the final variable we are requesting you to calculate? "In Finland, 256 people out of 10,000 are homozygous for the CCR5 allele mutation resulting in HIV resistance. Assuming the locus is in Hardy-Weinberg equilibrium, what is the expected genotype frequency of heterozygous carriers for the CCR5 mutation?"
- Through PCR, we have determined the PER3 genotypes for a class of students as follows: H4/H4 = 125 individuals; H4/H5 = 90 individuals and H5/H5=85 individuals. What is the frequency of the H5 allele in the class? Select only one answer. 1. 0.32 2. 0.24 3. 0.57 4. 0.19 5. 0.49 6. 0.43 7. 0.14With the many high throughput experiments that are used in biomedical research, how are some ways to integrate those datasets using systems biology? For example, if you had a microarray dataset that annotated gene expression levels and a proteomics dataset that identifed protein interactions, how could you jointly use both datasets to identify markers for a disease? Explain each step.What is the difference between a random sample and a composite sample? When would each be used?
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- If, for an observed data set, a specified gene, and two phenotype classes (disease and wild type), then the number of degrees of freedom for the chi-square goodness of fit test when studying the F2 generation is: a) 0 b) 3 c) -1 d) 2 e) 1Explain the similarities and differences between the procedures used for the coarse-scale mapping and fine-scale mapping of QTLs through controlled crosses, as was accomplished for QTLs involved with tomato size.if you encounter an unknown disease in humans and would like to understand the genetic mechanism for this disease so that an effective and targetted treatment approach can be developed , what will be the best strategy or steps to accomplish the goal? NB :answer in at most 4 sentences.
