Given the undecapeptide un sequenced Ala2, Arg, Glu, Lys, Met, Phe, Ser, Thr, Trp, Val. Edman Degradation identified Ala. It is further analyzed and degraded to four fragments using trypsin- catalyzed hydrolysis and yielded the following Ala – Glu – Arg ;Thr – Phe – Lys ; Lys ; and Met – Ser – Trp – Val . To further analyze the undecapeptide A.A Sequence, Chymotrypsin -catalyzed hydrolysis identified two fragments Ala – Arg – Glu – Phe – Thr and Lys – Met – Ser – Trp – Val and lastly treatment with cyanogen bromide identified two fragments: Ala – Arg – Glu – Lys – Met – Phe – Thr – Val; and Trp – Ser what is the name of the undecapeptide?

Given the undecapeptide un sequenced Ala2, Arg, Glu, Lys, Met, Phe, Ser, Thr, Trp, Val. Edman Degradation identified Ala. It is further analyzed and degraded to four fragments using trypsin- catalyzed hydrolysis and yielded the following Ala – Glu – Arg ;Thr – Phe – Lys ; Lys ; and Met – Ser – Trp – Val . To further analyze the undecapeptide A.A Sequence, Chymotrypsin -catalyzed hydrolysis identified two fragments Ala – Arg – Glu – Phe – Thr and Lys – Met – Ser – Trp – Val and lastly treatment with cyanogen bromide identified two fragments: Ala – Arg – Glu – Lys – Met – Phe – Thr – Val; and Trp – Ser what is the name of the undecapeptide?

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter10: From Proteins To Phenotypes

Section: Chapter Questions

Problem 10QP: b. Compounds A, B, C, and D are known to be intermediates in the pathway for production of protein...

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In a mixed heteropolymer experiment, messages were createdwith either 4/5C:1/5A or 4/5A:1/5C. These messages yielded proteinswith the amino acid compositions shown in the followingtable. Using these data, predict the most specific coding compositionfor each amino acid.4/5C:1/5A 4/5A:1/5CPro 63.0% Pro 3.5%His 13.0% His 3.0%Thr 16.0% Thr 16.6%Glu 3.0% Glu 13.0%Asp 3.0% Asp 13.0%Lys 0.5% Lys 50.0% 98.5% 99.1%
In studies using repeating copolymers, AC . . . incorporates threonine and histidine, and CAACAA . . . incorporates glutamine, asparagine, and threonine. What triplet code can definitely be assigned to threonine?
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Treatment of a polypeptide by 2-mercaptoethanol yields two polypeptides that have the following amino acid sequences: Ala-Phe-Cys-Met-Tyr-Cys-Leu-Trp-Cys-Asn Val-Cys-Trp-Val-Ile-Phe-Gly-Cys-Lys Chymotrypsin-catalyzed hydrolysis of the intact polypeptide yields polypeptide fragments with the following amino acid compositions: (Ala, Phe) (Asn, Cys2, Met,Tyr) (Cys, Gly, Lys) (Cys2, Leu,Trp2,Val) (Ile, Phe,Val) Indicate the positions of the disulfide bonds in the original polypeptide.
Treatment of a polypeptide by 2-mercaptoethanol yields two polypeptides that have the following amino acid sequences: Ala-Phe-Cys-Met-Tyr-Cys-Leu-Trp-Cys-Asn Val-Cys-Trp-Val-Ile-Phe-Gly-Cys-Lys Chymotrypsin-catalyzed hydrolysis of the intact polypeptide yields polypeptide fragments with the following amino acid compositions: (Ala, Phe) (Asn, Cys2, Met,Tyr) (Cys, Gly, Lys) (Cys2, Leu,Trp2,Val) (Ile, Phe,Val) Indicate the positions of the disulfide bonds in the original polypeptide. I don't understand how the order of amino acids in Step 2 was arranged. Please explain. Thank you.
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