Determine the pI of the peptide H2N-Ala-Lys-Ser-Arg-COOH at pH 11, please explain why some pKas are used in the solution of the problem while others are not.

Q: Under certain conditions, peptide bond formation rather than peptide bond hydrolysis is…

A: Peptide bond formation- A peptide bond is a chemical bond formed between two molecules when the…

Q: Both hsp60-like and hsp70 molecular chaperonesshare an affinity for exposed hydrophobic patches on…

A: Molecular chaperones are defined as the proteins that aid or help in the folding or unfolding of…

Q: I. Analysis of a peptide antibiotic purified from a strain of Bacillus brevii resulted in the…

A: The twenty amino acids are classified into majorly the following classes: Non-Polar(Aliphatic and…

Q: A. Write the structure of the following peptide at pH 5.0 and calculate its net charge at this pH.…

A: Hi. Thank you for the question. As per the honor code, We'll answer the first question since the…

Q: The peptide with sequence GVPLT has antioxidant properties.    Draw the chemical structure of this…

A: A polypeptide is a long-chain polymer, which is made up by joining several amino acids.

Q: Draw the structure in chair form of N-acetyl neuraminic acid. State occurrence and biological…

A: Sialic acids are an amino sugar category made up of 9-carbon α-keto acids. They’re mostly present on…

Q: Calculate the pI for the following tri-peptide: Glu-Arg-Lys

A: pI or isoelectric point is the pH at which a peptide or molecule is electrically neutral. The pH of…

Q: Peptide Y is a polymorphic analogue of Peptide X. If peptide X with endorphin-like property was…

A: Streptococcal protease could be any of the serine protease. as streptococcus is the general source…

Q: Which types of ion exchange resin will the the peptide Ala-Glu-lle-Lys- Leu-Asp-Gly bind to at the…

A: Ion exchange chromatography consists of column with loaded resin that can exchange oppositely…

Q: In a sample solution given to be analyzed; Starch + Val-Gly-Ile-Trp-Lys-Gly-Ala-Gly-Val-Glu  Plan…

A: Peptide bond binds the amino acid together and forms a linear chain ,more than 10 amino acids are…

Q: Determine the net charge (to the nearest integer) on the following peptide at pH5 AND pH 12.…

A:

Q: proteins are deamidated in an aqueous solution to produce ammonium and aspartate, respectively, from…

A: Isoelectric focusing (IEF), also known as electrofocusing, is a technique for separating different…

Q: The sequence of a 29 aa long peptide can be determined from the following data. a) Treatment of the…

A: Amino acids are the molecules that join to form a protein structure. The bond formed between two…

Q: Discuss the absorption spectra of arginine

A: Absorption spectra were recorded covering wavelength range 200-900 nm using ultraviolet-visible…

Q: Hydrolysis of dodecapeptide P with the enzyme trypsin affords the following fragments: Glu-Ala-Lys,…

A: Trypsin cleaves the dodecapeptide at the carboxyl side of Lys or Arg. Chymotrypsin cleaves the…

Q: Fibrinogen contains tyrosine- O - sulfate. Propose an activated form of sulfate that could react in…

A: Tyrosine O-sulfation of protein is a post-translational modification that mostly occurs in…

Q: Draw the structure of the pentapeptide Gln-Trp-His-Glu-Tyr that would predominate in acqueous…

A: Amino acids are made up of two functional groups, an amino (-NH2) group, and a carboxyl (-COOH)…

Q: Give the general Adiar equation for the binding of a ligand to a dimeric protein. Explain further…

A: Cooperativity- It is a character of some multi-subunit enzymes, where different subunits has…

Q: PLEASE DRAW the structure of the peptide: Val-His-Leu-Thr-Pro-Val-Glu-Lys-Ser-Ala-Val-Thr and…

A: Amino acids are the biomolecules that are made up of the amino group and a carboxyl group. The amino…

Q: What amino acid/s is/are isolated when Ala-Lys-Val-Phe—His-Tyr-Gly is treated with trypsin and…

A: Trypsin and chymotrypsin are serine proteases. Both these proteases catalyze the hydrolysis of…

Q: Pyrrolysine (Pyl, O) and Selenocysteine (Sec, U) are two uncommon amino acids. Knowing that these…

A: Amino acids are monomers that make up proteins. 20 different amino acids are commonly found in…

Q: The following peptide that has been acetylated at the C-terminus: CH3C(O)-GEEGH-NH2 Plot the…

A: Titration is a very useful procedure to estimate the concentration of any unknown compound in a…

Q: Draw the structural formula for the pentapeptide segment being synthesized. (Val-Thr-Arg-Pro-Glu)…

A: Protein is one of the major macromolecules that are essential for the normal functioning of the…

Q: An enzyme that catalyzes disulfide– sulfhydryl exchange reactions, called protein disulfide…

A: Protein disulfide isomerase or PDI is an enzyme that breaks sulfide bonds and is found in the…

Q: Calculate the overall net charge of the following polypeptide at pH = 2.0…

A: Amino acids are compounds containing carbon, hydrogen, oxygen and nitrogen. They are monomers…

Q: The tripeptide Glu-Pro-Arg (EPR) which is a product of Lactobacillus casei fermentation of milk was…

A: The given peptide is composed of three amino acids and it will be called tripeptide. The tripeptide…

Q: Draw the structure of the pentapeptide aspartic acid-serine-lysineUglutamic acidUtyrosine. Assume…

A: Protein is a polymer of amino acids connected together via peptide bond. Protein is the functional…

Q: In the serine protease triad, the proximity of an aspartatecarboxylate group to the imidazole group…

A: A serine protease triad is referred to as the protease that catalyzes the hydrolysis of the peptide…

Q: describe a detailed experimental procedure for the chemical synthesis of proteins with the…

A: Proteins are vital biomolecules that plays key role in biochemical pathways. It is synthesized in…

Q: Calculate the overall net charge of the following polypeptide at pH = 2.0…

A: The charge calculation on peptides is carried out by looking at the ionizable groups. Charge on the…

Q: The amino acid that is often used as a tag (in a run of 6-8 of this amino acid in a row) for protein…

A: Living cells have a complex system for protein synthesis. Ribosomes synthesize amino acid chains.…

Q: Consider a hexapeptide of the sequence thr asn glu trp lys gln. After complete hydrolysis, which…

A: Asked : Amino acid which elutes first

Q: Correlation between lipid profile and Covid-19.Explain this statement.

A: In December 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was discovered…

Q: Calculate the net charges of the following peptides at pH 7.4. Indicate which amino acids bear…

A: A peptide is formed by the combination of two or more amino acids. Each amino acid has an acidic…

Q: What is the principal form of arginine at pH 8.0? Approximately what fraction is in this form?

A: Arginine is a basic amino acid which contains an alpha amino group, an alpha carboxylic group and a…

Q: Hydrolysis of β-endorphin (a peptide containing 31 amino acid residues) produces the following…

A: This peptide is composed of standard amino acids. By treatment with various reagents such as DFNB,…

Q: The following sequence of amino acids are part of adult hemoglobin from the N-terminus. DRAW THE…

A: Amino acids are the molecules that join to form a protein structure. The bond formed between two…

Q: For the peptide Ala-Cys-His-Ile-Leu-Asp a. Write the single letter code for the amino acid residues…

A: A peptide is a compound which consists of two or more amino acids which are linked in a chain where…

Q: For a peptide with a sequence listed below. Lys-Gln-Val-Arg-Glu-Phe-His-Asn-Asp-Tyr 1) Estimate the…

A: Peptides are short strings of amino acids, typically comprising 2-50 amino acids. Amino acids are…

Q: Analysis of a peptide antibiotic purified from a strain of Bacillus brevii resulted in the following…

A: Average mol weight of one amino acid is 110D. The peptide is of 1200D. This means that the peptide…

Q: In a paragraph form, provide the experimental procedures in removal of the carbon dioxide present in…

A: Proteins are composed of amino acids in which amine group of one amino acid linked to carboxyl group…

Q: Please propose a method to synthesize the following peptide.  Leu.Gly.Ala  (automated synthesis…

A: Automated solid-phase peptide synthesis (SPPS) is a technology that is suitable technology in order…

Q: Show the steps involved in a Merrifield synthesis of Phe-Ala-Val.

A: In the Merrifield solid phase method, the synthesis of peptide is forwarded with the growing amino…

Q: you have the following peptide Arg-Ile-Pro-Leu-Asp-Lys-Glu The net charge on this peptide at pH 7.0…

A: Amino acids are biomolecules that are comprised of two functional groups, these are an amino group…

Q: Similarly, hypoxanthine (HX) can be used to label purine residues. As in Problem 4, write reactions…

A: It is given that hypoxanthine can be used to label the purine residues. Hypoxanthine always pair…

Q: When the amino acid sequences of insulin isolated from differentorganisms were determined, some…

A: Nucleotides are natural molecules comprising of a nucleoside and a phosphate. They fill in as…

Q: The trypsin enzyme is able to hydrolyze a peptide substate at the carboxyl side of an Arg or Lys…

A: Enzymes are protein molecules that increase the rate of enzyme reactions by decreasing the…

Q: The peptide aspartyl-glutamyl-leacyl-threony-alanine, shown in the sketch drewing window, has…

A: At low pH, a peptide will be fully protonated as the pH increases more than pKa of an ionizable…

Q: Based on the pk table for amino acids (Table 1.1), draw the structures with net charge, and the…

A: Acid strength is the tendency of an acid to dissociate and donate a proton. The value of pKa of an…

Nucleotides

It is an organic molecule made up of three basic components- a nitrogenous base, phosphate,and pentose sugar. The nucleotides are important for metabolic reactions andthe formation of DNA (deoxyribonucleic acid) and RNA (ribonucleic acid). 

Nucleic Acids

Nucleic acids are essential biomolecules present in prokaryotic and eukaryotic cells and viruses. They carry the genetic information for the synthesis of proteins and cellular replication. The nucleic acids are of two types: deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). The structure of all proteins and ultimately every biomolecule and cellular component is a product of information encoded in the sequence of nucleic acids. Parts of a DNA molecule containing the information needed to synthesize a protein or an RNA are genes. Nucleic acids can store and transmit genetic information from one generation to the next, fundamental to any life form.