Glucogenic amino acids degrade carbon skeleton to pyruvate or oxaloacetate while ketogenic amino acids degrade carbon skeleton into acetyl CoA or acetoacetyl CoA. True or False
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- Study Figure 19.18 and decide which of the following statements is false. Pyruvate dehydrogenase is inhibited by· NIADH. Pyruvate dehydrogenase is inhibited by AΤΡ. Citrate synthase is inhibited by NADH. Succinyl-CoA activates citrate synthase. Acetyl-CoA activates pyruvate carboxylase.Please explain the role of pantothenic acid-derived CoA as a carrier of acetyl group in carbohydrate metabolism.Although both acetyl-CoA and succinyl-CoA are high-energy thioesters, their chemical energy is used in distinct ways. Elaborate.
- The carboxylation of acetyl CoA to synthesize malonyl CoA by acetyl CoA carboxylase requires assistance from Vitamin K Vitamin D Vitamin B5 Vitamin 87Lysine is degraded to acetoacetyl-CoA then to acetyl-CoA, and is described as a _______ amino acid. a.polar b.glucogenic c.keto-gluco d.ketogenicList reaction or pathways of fatty acid oxidation and biosynthesis affected by insulin and glucagon.
- Elevated levels of acetyl-CoA will act as an effector for which of the following enzymes? more than one can be correct Pyruvate carboxylase. Pyruvate kinase Pyruvate dehydrogenase. Citrate synthase a-Ketoglutarate dehydrogenase.True or false The conversion of pyruvate to acetyl coa requires energy input into the format of atpIndicate whether each of the following statements is true or false. If false, correct the statement or provide a brief explanation for why it is false. Malonyl-CoA inhibits carnitine acyltransferase II , thus slowing transport of fatty acyl-CoA into mitochondrial matrix.
- True or falseKetone body synthesis requires transportation of acetyl-CoA through the inner mitochondrial membraneIndicate what will happen ( increase, decrease or no effect) tothe activity of the enzyme or rate of the metabolic pathway in the given conditions a. release of glucagon in the blood to the activity of carnitine acyl transferase 1 b. high malonyl CoA to the activity of carnitine acyl transferase I C. Epinephrine to the activity og glycogen synthase d. high citrate to the activity of acetyl CoA carboxylase e. high acetyl CoA to ketogenesisWhich of the following reactions required dihydrolipoyl dehydrogenase? Oxidative decarboxylation of pyruvate Oxidative decarboxylation of a-ketoglutarate Both A and B Neither A nor B Fatty acid biosynthesis is stimulated by: Decreased levels of citrate Increased levels of palmitoyl-CoA Increased levels epinephrine Increased levels of AMP All of the above None of the above
