Starting from the enantiomerically pure alkyl chloride, provide a two-step synthesis to arrive at the racemic mixture of epoxides shown below as the major products.H3C,,+ enantiomerCH3H3CCI

->First of all there occur elimination reaction in presence of base and alkene formed. -> Then…

Answered: H3C,,, + enantiomer CH3 H3C CI

Science

Chemistry

H3C,,, + enantiomer CH3 H3C CI

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter22: Carbonyl Alpha-substitution Reactions

Section22.SE: Something Extra

Problem 20MP

See similar textbooks

Related questions

Q: How long (in hours) must a current of 4.61 amps be passed to produce 79.5 g of copper metal from a…

A: Given:: Current i= 4.61 A Mass of Cu = 79.5 g Molar mass of Cu= 63.55 g mol-1 Time t= ?

Q: The Cs-131 nuclide has a half-life of 30 years. After 120 years, 5.2 g remain. What is the original…

Q: For a gas sample whose volume is 3.50 L at 300 K., what will be the volume at 390 K? O 0.220 L O 269…

Q: Explain the trend that bond formation does to atomic order by selecting all those that apply.…

A: Correct option is C

Q: [References] a. Cu-67 decays by beta decay. What are the atomic symbol and mass number of the…

A: Given, a. Cu-67 decays by beta decay. b. F-18 decays by positron emission. c. Sn-111 decays by…

Q: How many kilojoules of energy are generated when in 91.4 grams of NO(g) reacts according to the…

Q: Write the full clectron configuration for P. full electron configuration: Is2°2p°3;?3p6 What is the…

Q: You have a bottle of 0.15 M H2CO3 a. Write the name of the compound ________________ b. If the…

Q: EXPERIMENT: SIMPLE BATCH DISTILLATION I want theory background for this experiment

A: The answer is given below

Q: Part D Complete previous part(s) Part E Find the percent dissociation of a 0.130 M solution of a…

A: Given: The concentration of the weak monoprotic acid = 0.130 M The Ka of the acid = 0.15 We have to…

Q: percent change

Q: 2.) If a 50 grams of an ideal monoatomic gas has its volume doubled and the pressure is reduced to…

A: The internal energy of the system is the sum of all types of energy of the system. During the change…

Q: 6. Iron coated with zinc to prevent corrosion is known as iron. a) protected b) cathode iron cast d)…

A: The answer is given below

Q: Given Zn(s) and AL(s), what observations would you make when combining AL(s) with ZnSO4(aq), and…

A: when combining Al(s) with ZnSO4(aq) then the reaction will take place because Aluminium is more…

Q: Complete the following nuclear bombardment equation by filling in the nuclear symbol for the missing…

Q: 0-5 HCN Ka = 4.9 X 10-10 HClO2 Ka = 1.1 X 10-2 The…

A: Buffer range is the range of pH which is used for the determination of the working of buffer…

Q: A voltaic cell consists of an Al/Al3+ half-cell and a Fe2+/Fe3+ half-cell. The standard reduction…

Q: why do we need spindle cide in viscometer ?

A: By the help of Spindle (an immersed element) The Viscometer rotates a sensing element which…

Q: In the electrolysis of molten LiF, which product forms at the anode?

A: Given: Electrolysis of molten LiF.

Q: CH3 LIAIH, TCI

Q: In carboxylic acids, electrons__________ groups enhance acidity. A. Transferring B. Donating…

Q: A solution is made by dissolving 0.706 mol of nonelectrolyte solute in 781 g of benzene. Calculate…

A: Given: The number of moles of the nonelectrolyte solute dissolved in benzene = 0.706 mol The mass of…

Q: Find the pH of a 0.145 M HCIO2(aq) solution. For HCIO2, Ka = 0.011. O 0.84 O 1.46 O 1.34 O 1.40

A: Given: Concentration of HClO2 = 0.145 M And Ka of HClO2 = 0.011

Q: A student placed 16.0 g of glucose (C6H12O6) in a volumetric flask, added enough water to dissolve…

A: Given: Mass of glucose in the initial solution = 16.0 g. Volume of initial solution = 100 mL = 0.100…

Q: An electrochemical cell is constructed in which the silver ions in silver chloride are reduced to…

A: Given, A current of 0.500 A is passed through the cell for 101 minutes. The mass of copper metal…

Q: Provide the starting material for the following transformation 1. Оз ? 2. Zn H20 A B D A

A: In this question, we have to provide the starting material for the given transformation.

Q: QUESTION 5 Calculate the molarity of a solution made by dissolving 11.1 g CaCl2(s) in water to make…

A: Given that: Mass of CaCl2 = 11.1g Volume of solution = 400.ml = 400ml×1L/1000ml = 0.4L Molar mass…

Q: Americium-241 is widely used in smoke detectors. Calculate the amount of americium-241 consumed in a…

Q: 1. Which of the following describes an oxidation? a) loss of electrons or loss of oxygen b) loss of…

Q: A voltaic cell consists of an Mn/Mn2+ half-cell and a Cd/Cd2+ half-cell. Calculate [Mn2+] when…

Q: Calculate the value of [OH] from the given [H3O*] in each solution and label the acidic or basic: a.…

A: Given : We have to calculate the concentration of hydroxide ion.

Q: to cysteine residues in protein active sites. What glycolytic enzyme would be affected? As a result,…

A: A)In the range of metal concentrations analysed we found that only hexokinase and…

Q: 12.) Which of the following is NOT true for the kinetic molecular theory A.) The volume occupied by…

A: * Kinetic energy of gas molecules is related to the motion of molecules . * Greater the…

Q: How are the following aspects of a reaction affected by the addition of a catalyst? Increased…

A: Addition of catalyst does not change position of equilibrium it can decreases activation energy of…

Q: The mass spectrum of 4,5,6-trimethylheptan-3-one (drawn below) has 3 major peaks at 113, 86 & 57…

A: A question based on mass spectrum that is to be accomplished.

Q: Provide a mechanism for the following transformation. NH2 NaNO2/HCI/H,0 OH CH3 H3C- -CH3 H3C CH3 CH3…

A: Given : We have to make the product for the given reaction.

Q: A thermally activated reaction is completed in 5 seconds at 600 °C but requires 15 minutes for…

Q: Q1. A. How CO, can be converted to value-added products mediated by ionic liquids such as CO,…

A: Acording to question we will discuss about the conversion of CO2 to value added products and what…

Q: The maximum theoretical mass of product in a certain reaction is 20.0g, but only 15g is actually…

Q: 7. In aqueous solution, hydrazine is a base that can accept two protons: N2H4(aq) + H2O(1)…

A: #7 (a): Since Kb2 << Kb1, the OH-(aq) contribution is mainly due to the 1st hydrolysis…

Q: The molecule (CH3)2N-PF2 has two atoms that can act as Lewis bases. With boron compounds, BH3…

A: According to HSAB principle: Hard acid prefers to bind with hard base. Soft acid prefers to bind…

Q: Explain, with the help of structures and curved arrow mechanisms, why trans-2-chloro-…

A: Given:

Q: Describe a series of reactions that could be used to create butanoic acid from butene. Include the…

Q: A reaction is initiated by mixing suflur dioxide and oxygen. This reaction forms sulfur trioxide. 2…

A: Given-> Initial Concentration of SO2 = 0.100 M Initial Concentration of O2 = 0.150 M Final…

Q: In reactions with copper and cobalt salts, preliminary ionization of acidic forms of barbiturates:…

A: correct option is A(Required )

Q: Two kinetics trials are performed at the same temperature with [S2O82-] held constant. The first…

A: Given: The concentration of S2O82- is kept constant. The concentration of I- is quadrupled reducing…

Q: A sample contains 4.70 * 10-4 mol of gold, Au. How many atoms of gold are in the sample?

Q: Find the AHn for the following reaction: B2 H6 (g) + 6 Cl2(9) → 2 RC13(g) + 6 HCl(g) given the…

A: B2H6(g) + 6 Cl2(g) --> 2BCl3(g) + 6HCl(g)

Q: Two substances, iron and granite, initially at different temperatures, come into contact and reach…

Q: Consider the titration of 30.0 mL of 0.315 M weak base B (Kb = 1.3 x 10⁻¹⁰) with 0.150 M HI. How…

A: At halfway point , half moles of base are neutralized by acid , HI . So, we would calculate moles…

Concept explainers

Alkanes and Cycloalkanes

Alkanes are saturated organic compounds which are made up of C and H atoms. Alkanes have the general formula of CnH2n+2. Alkane contains sp3 hybridized carbon atoms with four sigmas (σ) bonds & every hydrogen atom is connected with one of the carbon atoms. The size of the alkane could be determined by the number of carbon atoms located in it.

Question

Starting from the enantiomerically pure alkyl chloride, provide a two-step synthesis to arrive at the racemic mixture of epoxides shown below as the major products.
H3C,,
+ enantiomer
CH3
H3C
CI

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

SEE SOLUTION Check out a sample Q&A here

Step 1

VIEW

Step 2

VIEW

Step by step

Solved in 2 steps with 1 images

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.

Similar questions

(a) Give a mechanism for this reaction, showing how the two products arise as aconsequence of the resonance-stabilized intermediate.(b) The bromination of cyclohexene using NBS gives only one major product, as shown onthe previous page. Explain why there is no second product from an allylic shift.
A student in Ochem proposed the following synthesis. Explain the problem with this approach and provide the necessary reagents to convert halohydrin A to alkene B (more than one step is required) in addition provide the product after each step. Provide the mechanism and expected actual final product from the reaction of halohydrin A with LDA
Give the major organic product of the following reaction sequences (d & e).
The (+) - aureol is a natural product that has shown selective activity against certain colon and lung cancer cell lines. It is postulated that a key step in the biosynthesis of this substance is the conversion of carbocation A into B. Propose a possible mechanism for this transformation (MUST show the corresponding arrows).
Propose a detailed mechanism for the transformations presented. represent the Intermediate structure A.
Both menthyl chloride and neomenthyl chloride (structures shown below) undergo E2 elimination in the presence of EtONa in ethanol. Provide the possible product(s). Which substrate reacts faster in term of overall reaction rate? Explain why.
Propose a pericyclic mechanism to account for the following transformation:
Acid-catalyzed hydrolysis of the following epoxide gives a trans diol. Of the two possible trans diols, only one is formed. How do you account for this stereoselectivity?
Acetoxybenzene (PhOC(=O)OCH3) is much less reactive than ethoxybenzene (PhOCH2CH3) in electrophilic aromatic substitution reactions. Suggest an explanation for this result, based on an analysis of the inductive and resonance electronic effects of the two substituents on the stability of theWheland intermediate for para substitution by an electrophile E+
Provide the major products and show stereochemistry if needed.
The Favorskiireaction involves treatment of an a-bromo ketone with base to yield a ring-contracted product. For example, reaction of 2-bromocyclohexanone with aqueous NaOH yields cyclopentanecarboxylic acid.what is the mechanism of the reaction.
Muscone synthesis is possible via an intramolecular Prins reaction. The starting point is cyclododecatriene, which his subjected topartial ozonolysis.With one aldehyde group protected,the other is reacted with isobutenyl magnesium chloride, and the protecting group is hydrolysed off. Then follows what is formally a Prins reaction,and etherification results in cyclisation to the bicyclic dihydropyran. Hydrogenation (at high T) finally gives racemic muscone. a. How to remove the protective group? b. What happens if you don't use a protective group?