Hb Waterloo has an AspG1 (94)a to Gln mutation. Which of the following statements is TRUE? It has a high affinity for O2 because a hydrogen bond in the T state is broken. It has a low affinity for O2 because a hydrogen bond in the R state is broken. The Bohr effect is diminished due to the loss of the primary binding site of the Bohr proton. The mutant has a lower affinity for O2 due to the loss of a hydrogen bond present in the T state. O Cooperativity in the mutant is increased because the mutation occurs in the switch region.
Hb Waterloo has an AspG1 (94)a to Gln mutation. Which of the following statements is TRUE? It has a high affinity for O2 because a hydrogen bond in the T state is broken. It has a low affinity for O2 because a hydrogen bond in the R state is broken. The Bohr effect is diminished due to the loss of the primary binding site of the Bohr proton. The mutant has a lower affinity for O2 due to the loss of a hydrogen bond present in the T state. O Cooperativity in the mutant is increased because the mutation occurs in the switch region.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:Hb Waterloo has an AspG1 (94)a to Gln mutation. Which of the following statements is TRUE?
It has a high affinity for O2 because a hydrogen bond in the T state is broken.
It has a low affinity for O2 because a hydrogen bond in the R state is broken.
The Bohr effect is diminished due to the loss of the primary binding site of the Bohr proton.
The mutant has a lower affinity for O2 due to the loss of a hydrogen bond
present in the T state.
Cooperativity in the mutant is increased because the mutation occurs in the switch region.
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