HO. HO. HO Он O2 :ö" но Он бон PGF20 PGG2 A unstable intermediate ö-ö:

Organic Chemistry: A Guided Inquiry
2nd Edition
ISBN:9780618974122
Author:Andrei Straumanis
Publisher:Andrei Straumanis
Chapter13: Substitution
Section: Chapter Questions
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PGF (Section 4.15) is synthesized in cells from arachidonic acid (C20H32O2) using a cyclooxygenase enzyme that catalyzes a multistep radical pathway. Part of this process involves the conversion of radical A to PGG2, an unstable intermediate, which is then transformed to PGF and other prostaglandins. Draw a stepwise mechanism for the conversion of A to PGG2. (Hint: The mechanism begins with radical addition to a carbon–carbon double bond to form a resonance-stabilized radical.)

HO.
HO.
HO
Он
O2
:ö"
но
Он
бон
PGF20
PGG2
A
unstable intermediate
ö-ö:
Transcribed Image Text:HO. HO. HO Он O2 :ö" но Он бон PGF20 PGG2 A unstable intermediate ö-ö:
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