How does the normal p53 protein inhibit cancer development?

Q: What is the difference between saying that cancer is inherited and saying that the predisposition to…

A: A hereditary inclination or hereditary weakness to malignant growth implies that an individual has…

Q: What is the link between epigenetics and cancer?

A: Epigenetics is considered as the study in which the gene shows its behavior according to the…

Q: How is an inmortal cancer cell line different from a regular cancel cell line ?

A: Cancerous cells : In our body cell division and differentiation is a highly regulated and controlled…

Q: Why is it only the risk for cancer that is inherited?

A: ANSWER --Introduction -- Genes are part of the chromosomes , carry instructions to make proteins…

Q: What enzyme is upregulated in cancer that overcomes cell senescence?

A: Various type of tumor suppressor genes and oncogenes regulate senescence in normal cell.…

Q: How can researchers pinpoint the particular driver mutations most responsible for the cancer…

A: The development of cancer is an evolutionary process at the cellular level. Several mutations…

Q: What are the biggest challenges that mutations pose to oncologists and cancer biologists who seek to…

A: Mutations are one of the biggest challenges to the Oncologists and cancer biologists who wish and…

Q: What are the normal functions of the BRCA1 tumor suppressor gene?

A: The BRCA1 gene codes for the protein that causes breast cancer type 1. BRCA1 is a human tumour…

Q: Why are people more likely to develop cancer as they age? Why does inheriting a mutation increase…

A: Cancer is the name given to a collection of related diseases.In all types of cancer,some of the…

Q: What significance do BRCA1 and BRCA2 have in regard to developing cancer, and what types of cancer…

A: BRCA 1 & BRCA 2 are found pair in all the organisms where one gene is obtained from each of the…

Q: How do cancer cells acquire a potential for immortality?

A: The cancer cells are characterized by the ultimate power of division,  flooding the blood with…

Q: What is happening in all cancer? What process is this disrupting?

A: Cancer in simple term can be referred to a set of diseases which are caused by the production of an…

Q: What is the relationship betweenobesity and cancer?

A: Chronic diseases are the leading cause of mortality and morbidity and contribute significantly to…

Q: Which genetic cancer predisposition syndrome is caused by germ-line mutations in the p53 gene and is…

A: P53 is the tumor suppressor protein (TP53 in humans) which is also described as the guardian of the…

Q: Explain how Epigenetics are related with Cancer ?

A: Answer- Epigenetics is the change in the gene expression without changing the sequence of the DNA.

Q: How can oncogenes lead to cancer?

A: Oncogenesis is a complex, multifactorial process by which normal cells turn into malignant cells.…

Q: What is the role of the microenvironment in cancer development and progression?

A: Progression of cancer is the steps of progress of this disease, it includes many stages:  Stage I…

Q: What is the difference in an oncogene and tumor suppressor gene and how can each potentially lead to…

A: Cancer is group of diseases which are characterized by abnormal and unstoppable growth of cell and…

Q: What is the working of Tumor suppressor genes ?

A: There are two types of genes that are associated with tumors: Oncogenes: These genes when directly…

Q: What are stem cells? Which stem cell treatment can form a benign tumor? Please explain how benign…

A: Introduction :- Stem cells  are of various types : Totipotent  Pleuripotent  Multipotent…

Q: How mutations, chromosomal changes epigenetics, and environmental agents play roles in the…

A: Cancer cells breaks the most basic rule of cell behavior by which multicellular organism are built…

Q: What genes are involved in cancer?

A: Genes Involved In Cancer --- Genes  and Their Characteristics -- Genes are made up of pieces of DNA…

Q: What protein does the P53 code for and why is it important?

A: Answer :- The TP53 quality gives guidelines to making a protein called growth protein p53 (or p53).…

Q: What are the requirements for normal cell division? What are the requirements for cancer cells…

A: Mutation is defined as an erroneous change within the gene sequence of an organism that leads to a…

Q: How do normal cells protect themselves from accumulating mutations in genes that could lead to…

A: Studies reveal that the p53 protein instructs cells to under-go apoptosis when mutations in the DNA…

Q: How do cancers protect themselves from cell death?

A: Introduction :- A multicellular organism's life cycle must include cell death. Most cell deaths…

Q: How do oncogenes differ from tumor suppressor genes?

A: Oncogenes are a physically and functionally diverse set of genes, the protein products of which act…

Q: How Cancer Involves the Proliferation of a Clone of Cells?

A: When the cell division becomes out of control and cells starts accumulating it results in cancer.

Q: How does the multistep model of cancer explain the observation that sporadic cases of retinoblastoma…

A: Disease is a sickness or illness characterized by specific symptoms and signs. Cancer is a…

Q: Do more mutations necessarily mean that more cancer-causing genes are faulty? Why or why not?

A: Biotechnology is a wide range of studies where it uses its techniques with biological systems to…

Q: Why is the tumor microenvironment important to cancer progression?

A: Cancer progression requires metastasis which in turn is the ability of tumors to migrate within the…

Q: How are cancer cells different from normal cells?

A: Cancer cells are those cells which are divided abnormally and uncontrollably. There are many…

Q: What role do cell check points have in cancer ?

A: Cancer is a disease that is associated with uncontrolled division of cells and invasion of…

Q: What technique is used to identify genes involved in cancer formation ?

A:

Q: What is the relationship between the cell cycle and cancer production?

A: A cell is the fundamental, structural, and functional unit of the living cell bounded with a cell…

Q: What type of epigenetic changes are associated with cancer?

A: Epigenetic changes or modifications are important for maintenance of tissue specific gene…

Q: Can restoring tumor suppressor function, such as mutant p53 or pRb, be used to cure cancer? If…

A: The Cell division is the process through which one cell divides into two identical daughter cells.…

Q: What is a tumor suppressor? What is an oncogene?

A: Cancer is a diseased condition where the cells show abnormal growth and proliferation. The cancerous…

Q: How would our understanding of this regulation affect cancer prognosis and treatment?

A: The epithelial-mesenchymal transition (EMT) is a complex developmental process that allows cancer…

Q: What are the most common treatments of cancer?

A: Introduction: Uncontrolled cell division is a symptom of cancer. Tumors, immune system harm, and…

Q: What characterizes a cancer cell?

A: Introduction Loss of control over regulated mechanisms like division, differentiation, and apoptosis…

Q: Do mutations that cause cancer in an individual pass down to his/her offspring? What is the role of…

A: Cancer is the umbrella term for a group of diseases. Any of the body's cells begin to divide without…

Q: How do we know that malignant tumors arise from a single cell that contains mutations?

A: Malignant tumors are multicellular cell masses invading normal tissues and disrupting their function…

Q: Can you think of two ways in which the function of p53 can be disrupted?

A: P53 is a tumor suppressor gene which normally restrains growth and mutation in this causes loss of…

Q: What is haploinsufficiency? How might it affect cancer risk?

A: The term in genetics that explains the function of the dominant gene in the representation of…

Q: What are the most common side effects of cancer treatment?

A: Treatment Modalities for cancer 1. Surgery 2. Chemotherapy 3. Radiation Therapy 4. Biologic and…

Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.