(i) Draw and explain how SPO11 can generate double strand breaks. (ii) What would be the consequences to the outcome of meiosis if SPO11 is absent? Explain your reason.

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Chapter6: Cytogenetics: Karyotypes And Chromosome Aberrations
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Problem 14QP: Variations in Chromosome NumberAneuploidy Describe the process of nondisjunction and explain when it...
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Hundreds of DNA double strand breaks are created by SPO11, a topoisomerase type II like
protein.
(i)
Draw and explain how SPO11 can generate double strand breaks.
(ii)
What would be the consequences to the outcome of meiosis if SPO11 is absent?
Explain your reason.
Transcribed Image Text:Hundreds of DNA double strand breaks are created by SPO11, a topoisomerase type II like protein. (i) Draw and explain how SPO11 can generate double strand breaks. (ii) What would be the consequences to the outcome of meiosis if SPO11 is absent? Explain your reason.
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