Identify the partial sequence of events that occurs after the insulin binds to its receptor. 1. Phosphorylation of insulin receptor substrate (IRS-1) 2. Activation of the receptor tyrosine kinase activity 3. Activation of phosphodiesterase 4. Activation of phospholipase C 5. Phosphorylation of phosphatidylinositol 6. Activation of phosphatidylinositol-3 -kinase (P1-3 kinase) 7. Binding of Grb 2 8. Activation of a phosphatase 9. Dephosphorylation of pyruvate kinase 10. phosphorylation of pyruvate kinase
Identify the partial sequence of events that occurs after the insulin binds to its receptor. 1. Phosphorylation of insulin receptor substrate (IRS-1) 2. Activation of the receptor tyrosine kinase activity 3. Activation of phosphodiesterase 4. Activation of phospholipase C 5. Phosphorylation of phosphatidylinositol 6. Activation of phosphatidylinositol-3 -kinase (P1-3 kinase) 7. Binding of Grb 2 8. Activation of a phosphatase 9. Dephosphorylation of pyruvate kinase 10. phosphorylation of pyruvate kinase
Essentials of Pharmacology for Health Professions
7th Edition
ISBN:9781305441620
Author:WOODROW
Publisher:WOODROW
Chapter23: Endocrine System Drugs
Section: Chapter Questions
Problem 15CRQ
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Question
Identify the partial sequence of events that occurs after the insulin binds to its receptor.
1. Phosphorylation of insulin receptor substrate (IRS-1)
2. Activation of the receptor tyrosine kinase activity
3. Activation of phosphodiesterase
4. Activation of phospholipase C
5. Phosphorylation of phosphatidylinositol
6. Activation of phosphatidylinositol-3 -kinase (P1-3 kinase)
7. Binding of Grb 2
8. Activation of a phosphatase
9. Dephosphorylation of pyruvate kinase
10. phosphorylation of pyruvate kinase
- 2-7-1-4-3-9
- 1-7-3-5-6-8
- 2-1-6-5-8-9
- 2-7-1-6-5-8-9
- 2-7-4-6-1-8-10
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