Il-- Results from a single locus probe DNA fingerprint analysis for a man and woman and their four children are shown in the autoradiograph below. Which child is least likely to be the biological offspring of this couple? Explain Why?
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- A. HUMAN PEDIGREE CASE ANALYSIS1. One couple has three children with the following sexes and ages: one son (40 y.o.) and two daughters (35 y.o. and 33 y.o.), all of them have normal pigmentation. Another couple has a son (35 y.o) and a daughter (20 y.o.) and all of them also have normal pigmentation. Both couples have normal pigmentation. The younger daughter from the first couple married the son of the second couple and they had three children. Their eldest daughter (5 y.o.) has normal pigmentation while their only son (3 y.o.) and one daughter (1 y.o.) have albinism. a. Draw the pedigree of this family. Follow protocols in making a pedigree. Provide the genotype of all individuals in the pedigree. Please provide also the gene notation. b. What is the mode of inheritance of this trait? c. Justify your answer in letter (b).d. For their normal daughter, what is the probability that she is a carrier? Show solution. e. If they will have a fourth child, what is the probability that the…Please write your complete solution (paper). Albinism in humans is inherited as a simple recessive trait. Determine the genotypes of the parents and their children when albino male and normal femaleUse the following information to respond to the three questions posed below: (1) The proband (affected individual who led to the construction of the pedigree) exhibits the trait. (2) Neither her husband nor her only sibling, an older brother, exhibits the trait. (3) The proband has five children by her current husband. The oldest is a boy, followed by a girl, then another boy, and then identical twin girls. Only the second oldest fails to exhibit the trait. (4) Both parents of the proband show the trait. a. Construct a pedigree of the trait in this family. b. Determine how the trait is inherited (go step by step to examine each possible pattern of inheritance). c. Can you deduce the genotype of the probands husband for this trait?
- Please write your complete solution (paper). Albinism in humans is inherited as a simple recessive trait. Determine the genotypes of the parents and their children when a normal male and albino female have 2 normal and 2 albino children.6-8 as they’re all for the same chart Image 1 is phenotypes Image 2 are questionsCan someone show me why this is correct? I will like to see the possible genotypes and phenotypes together that proves the answer.
- If the proband (III-2) marries a carrier woman, what is the probability that they will have an affected son? affected daughter? (Please show complete solution. Thanks.)I need help in table 2 & 3 please Table 1 Phenotype O E O-E (O-E)^2 (O-E)^2 /E Disease, Male 304 433.875 129.875 16789.68 38.69 Disease, Female 267 433.875 166.875 26855.01 61.89 WT, Male 285 144.625 140.375 19705.14 136.25 WT, Female 301 144.625 156.375 24453.15 156.37 Total 1157 1157 393.20 DF 3 p-value 7.84 Expected progencies as per SLR MOI’s = 1:1 for both male and female Phenotype O E O-E (O-E)^2 (O-E)^2 /E Disease, Male 304 289.25 14.75 217.56 0.75 Disease, Female 267 289.25 22.25 495.06 1.85 WT, Male 285 289.25 4.25 18.06 0.06 WT, Female 301 289.25 11.75 138.06 0.46 Total 1157 1157 3.12 DF 3 p-value 7.84 Progenies are following SR MOI’s that parents have genotypes and progenies in ratio 1:1 In Table 2,…I need some help with this fill-in-the-blank problem. The answer choices are bolded and bracketed. Please see the attached photo to complete. 1. In the D2S441 locus, Sophie's allele [10, 12] is maternal and her allele 10 is paternal from [Sam or Bill only, Sam or Harry only, Bill or Harry only, Sam Bill or Harry (either 3)]. 2. Sophie's allele 13 for D19S433 is [maternal, paternal] and her allele 14 could have come from [Sam and Bill only, Sam and Harry only, Bill and Harry only, Sam Bill or Harry (either 3)]. 3. In the FGA locus, Sophie's allele [21, 22] is maternal and her other allele could have come only from [Sam, Bill, Harry]. 4. Based on all STRs in the 3 panels we studied, it is clear that [Sam, Bill, Harry] is Sophie's father. He has one allele of Sophie's alleles for all STR loci 5. Would these results stand in court as proof paternity: [Yes or No] 6. This type of DNA profiling can also be used to determine maternity. Is there any doubt that Donna is Sophie's biological…
- What can you tell about the person that this karyotype is from? Choose ALL that apply. The person is female The person is male The person has Down's syndrome The cell the DNA was taken from has gone through S phase The cell the DNA was taken from was in G1 phase of cell cycle The person has cancer Nondisjunction occurred here This is from a body cell This is from a gameteRrxRR Genotyperatioofoffspring___________________ Phenotyperatioofoffspring__________________DIHYBRID CROSS Heterozygous Yellow and heterozygous round seed crossed with homozygous yellow and heterozygous round seed. Find the following: 1. Alleles of both parents (given problems) 2. Genotype 3. Phenotype ratio 4. Write the punnet square -Please answer this on the paper and explain the answer step by step. Thank you asap