Imagine that you are working with DNA sequences of membrane proteins) and have the technology to genetically engineer/alter the existing sequence and you can express this particular protein in a yeast cell model. You also have the power to track and visualize where the genetically engineered proteins traffic in your model system. You engineer an ER signal sequence to the amino-terminal end of a normally cytosolic protein. Which best describes the fate of this protein? The protein is degraded The protein remains in the cytosol The protein is translocated through the ER membrane translocon channel, N' end first The protein is translocated through the ER membrane translocon channel, C' end first

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Imagine that you are working with DNA sequences of soluble proteins (not
membrane proteins) and have the technology to genetically engineer/alter the
existing sequence and you can express this particular protein in a yeast cell model.
You also have the power to track and visualize where the genetically engineered
proteins traffic in your model system.
You engineer an ER signal sequence to the amino-terminal end of a normally
cytosolic protein.
Which best describes the fate of this protein?
The protein is degraded
The protein remains in the cytosol
The protein is translocated through the ER membrane translocon channel, N'
end first
The protein is translocated through the ER membrane translocon channel, C' end
first
Transcribed Image Text:Imagine that you are working with DNA sequences of soluble proteins (not membrane proteins) and have the technology to genetically engineer/alter the existing sequence and you can express this particular protein in a yeast cell model. You also have the power to track and visualize where the genetically engineered proteins traffic in your model system. You engineer an ER signal sequence to the amino-terminal end of a normally cytosolic protein. Which best describes the fate of this protein? The protein is degraded The protein remains in the cytosol The protein is translocated through the ER membrane translocon channel, N' end first The protein is translocated through the ER membrane translocon channel, C' end first
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