In most species of mammals, the O2 affinity of a fetus’s bloodhemoglobin is greater than that of its mother’s blood hemoglobin.However, mammal species are not all the same in the mechanismthat causes the affinities to be different. Specify three distinctmechanisms for the difference in affinity between fetal andmaternal blood hemoglobin. Considering the mechanism of the fetal–maternal difference in O2 affinity, would you say that the evolution of themechanism provides evidence for Jacob’s argument? Explain.

In most species of mammals, the O2 affinity of a fetus’s bloodhemoglobin is greater than that of its mother’s blood hemoglobin.However, mammal species are not all the same in the mechanismthat causes the affinities to be different. Specify three distinctmechanisms for the difference in affinity between fetal andmaternal blood hemoglobin. Considering the mechanism of the fetal–maternal difference in O2 affinity, would you say that the evolution of themechanism provides evidence for Jacob’s argument? Explain.

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Description: In most species of mammals, the O2 affinity of a fetus’s bloodhemoglobin is greater than that of its mother’s blood hemoglobin.However, mammal species are not all the same in the mechanismthat causes the affinities to be different. Specify three dist

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter11: The Blood

Section: Chapter Questions

Problem 1SQE

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The following graph shows partial saturation (Y) of myoglobin (Mb), adult hemoglobin (HbA) and fetal hemoglobin (HbF) as a function of partial oxygen pressure (in mmHg). Use it to answer the question: Fetal hemoglobin ( biological function: HbF) demonstrates lower p50 than adult hemoglobin (HbA). This adaptation has the following A. Allow fetal hemoglobin form pentamer subunits. B. HbF has lower affinity for for O2 compared to adult Hb C. Allow fetal hemoglobin to effectively intercept oxygen from mother's hemoglobin. D. Allow fetal hemoglobin to replace myoglobin in muscles
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The hemoglobin in mammalian blood is usually thought of simply as increasing the amount of O2 that can be carried by each litter of blood. Explain how the presence of hemoglobin in the blood also makes possible the rapid uptake of O2 by the blood as it flows through the lungs.
Which of the following best explains why fetal hemoglobin (HbF) has higher affinity for oxygen than HbA? a. HbF binds 2,3-bisphosphoglycerate with lower affinity b. One of the coordination positions of HbF is occupied by an Asp residue c. Oxygen binding is not cooperative in HbF d. The Fe-O bond is shorter in HbF e. The hemes of HbF and HbA have different structures
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When researchers first discovered that airflow through a bird’s paleopulmonal parabronchi is unidirectional, the question arose as to whether gas exchange is countercurrent, cocurrent, or cross- current. Some ingenious investigators carried out experiments in which they measured the efficiency of gas exchange between air and blood in duck lungs when parabronchial airflow was in its normal direction and when the direction of parabronchial airflow was artificially reversed. The efficiency did not change. How is this evidence against countercurrent and cocurrent gas exchange? How is this evidence for cross-current exchange?
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