In proteomics, peptidomics (and the other -omics techniques), hyphenated MS techniques are used, andcoupled with databases.(1) how are GC-MS, LC-MS, and MS-MS or MS" techniques different from each other?(2) For the MS instruments, two parameters are often considered - type of ionization and ion massdetection. Describe each.MS ParameterPrinciplelonizationESIMALDIFABlon mass detectionQuadrupoleTOFlon trapOrbitrap(3) What is a protein database? Give examples (and links) of some protein databases.

Since you have asked multiple questions, we will solve first one for you. For remaining questions,…

In proteomics, peptidomics (and the other -omics techniques), hyphenated MS techniques are used, and coupled with databases. (1) how are GC-MS, LC-MS, and MS-MS or MS" techniques different from each other?

In proteomics, peptidomics (and the other -omics techniques), hyphenated MS techniques are used, and coupled with databases. (1) how are GC-MS, LC-MS, and MS-MS or MS" techniques different from each other?

Principles of Instrumental Analysis

7th Edition

ISBN:9781305577213

Author:Douglas A. Skoog, F. James Holler, Stanley R. Crouch

Publisher:Douglas A. Skoog, F. James Holler, Stanley R. Crouch

Chapter28: High-performance Liquid Chromatography

Section: Chapter Questions

Problem 28.21QAP

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Concept explainers

Spectroanalytical Methods

Spectroanalytical methods measure the wavelength and intensity of radiations that are either emitted or absorbed by a molecular or atomic species. These methods are useful for evaluating the electronic or atomic arrangement of the molecules of a given analyte.

Question

In proteomics, peptidomics (and the other -omics techniques), hyphenated MS techniques are used, and
coupled with databases.
(1) how are GC-MS, LC-MS, and MS-MS or MS" techniques different from each other?
(2) For the MS instruments, two parameters are often considered - type of ionization and ion mass
detection. Describe each.
MS Parameter
Principle
lonization
ESI
MALDI
FAB
lon mass detection
Quadrupole
TOF
lon trap
Orbitrap
(3) What is a protein database? Give examples (and links) of some protein databases.

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pls answer the last 3

TOF

ion trap

orbitrap

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pls answer the next 3 pls

FAB

ion mass detection

quadrupole

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