In the nematode C. elegans, some worms have blisteredcuticles due to a recessive mutation in one of the bligenes. Someone studying a suppressor mutation thatsuppressed bli-3 mutations wanted to know if it wouldalso suppress mutations in bli-4. They had a strain thatwas homozygous for this recessive suppressor mutation,and its phenotype was wild type.a. How would they determine whether this recessivesuppressor mutation would suppress mutations in bli-4?In other words, what is the genotype of the wormsrequired to answer the question?b. What cross(es) would they do to make these worms?c. What results would they expect in the F2 if(1) it did act as a suppressor of bli-4?(2) it did not act as a suppressor of bli-4?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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In the nematode C. elegans, some worms have blistered
cuticles due to a recessive mutation in one of the bli
genes. Someone studying a suppressor mutation that
suppressed bli-3 mutations wanted to know if it would
also suppress mutations in bli-4. They had a strain that
was homozygous for this recessive suppressor mutation,
and its phenotype was wild type.
a. How would they determine whether this recessive
suppressor mutation would suppress mutations in bli-4?
In other words, what is the genotype of the worms
required to answer the question?
b. What cross(es) would they do to make these worms?
c. What results would they expect in the F2 if
(1) it did act as a suppressor of bli-4?
(2) it did not act as a suppressor of bli-4?

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