Individuals with Pompe disease lack the lysosomal _______. a. Glycogen phosphorylase b. Amylo-α(1→6)-glucosidase c. α(1→4)-glucosidase d. Glucose-6-phosphatase
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- If you fed a mouse a diet made up of exclusively Leucine, the mouse would eventually: A、Undergo extensive gluconeogenesis B、Enter ketosis C、Have a buildup of α-Ketoglutarate D、gain weight E、have a buildup of succinyl-CoAExplain why insulin is required for adipocytes to synthesize triacylglycerols from fatty acids.Can you answer all the parts to this question please List effectors of glycogen phophorylase: A. When blood [glucose] is high. B. When blood [glucose] is low.
- Patients with von Gierke’s disease (a glycogen storage disease) lack glucose-6- phosphatase activity. Two prominent symptoms of this disorder are fasting hypoglycemia and lactic acidosis. Can you explain why these symptoms occur?Explain the differences between a) glycogenolysis, b) gluconeogenesis, and c) glycogen synthesis. Mention what hormone(s) have a direct effect on each process.1) Gluconeogenesis refers to ________. A) the breakdown of glycogen B) the formation of glucose from noncarbohydrate sources C) the formation of glycogen. D) splitting of glucose to pyruvate E) fermentation of glucose to ethanol 3) Glycogenesis refers to ________. A) the breakdown of glycogen B) the formation of glucose from noncarbohydrate sources C) the formation of glycogen D) splitting of glucose to pyruvate E) fermentation of glucose to ethanol 3) Ketosis is a condition that can occur if A) ketone bodies instead of glucose are used for energy. B) too many ketones are ingested. C) too much protein is available in the diet. D) the brain is starved of glucose. E) low fat intake occurs.
- Glucose 6-phosphatase deficiency is a glycogen storage disease referred to as von Gierke disease. Which of the following symptoms would you NOT expect to see in patients with this disease? (A) severe fasting hypoglycemia (B) excess adipose triglyceride storage and low circulating levels of fatty acids (C) hyperammonemia (D) liver enlargement resulting from excess liver glycogen storage (E) lactic acidosis (F) gout(a) What amino acid, other than alanine, can be converted by transaminationto a gluconeogenic precursor? (b) Calculate the cost, in ATP equivalents, of converting two molecules of this amino acid to one molecule of glucose.what effect would an increase in glucose typically have on the activity of glycogen synthase
- Under conditions of stress, the hormone glucagon is synthesized and secreted from the α-cells of the pancreas. Please describe how glucagon can regulate the activity of glycogen phosphorylase and explain how this affects energy expenditure in human bodyWhich one of the following is NOT a metabolic effect of glucagon secretion? Select one: a. Increase in gluconeogenesis. b. Increased glycogenolysis. c. Increase in the activity of adenylate cyclase. d. Increased amino acid uptake by the muscles.Why does epinephrine stimulate glycolysis? I know why epinephrine stimulates glycogenolysis which is to release glucose stores. But epinephrine stimulating glycolysis seems counterintuitive as it would synthesize less glucose and more pyruvate?