The picture below is of an amino acid called lysine: H₂N. NH₂ OH Download During a period of starvation in an otherwise healthy human, the citric acid cycle in hepatic tissue (liver cells) is depleted of a crucial intermediate due to the upregulation of gluconeogenesis. Answer the following questions: A) What is that crucial citric acid cycle intermediate that has been depleted due to the upregulaton of gluconeogenesis? B) After lysine catabolism, do you expect its products to form substrates for gluconeogenesis? If so, why? If not, why not? C) During periods of starvation, which end-products of lysine catabolism can be used as an energy source to maintain brain function? In your answer, clearly indicate which answer belongs to which part.
The picture below is of an amino acid called lysine: H₂N. NH₂ OH Download During a period of starvation in an otherwise healthy human, the citric acid cycle in hepatic tissue (liver cells) is depleted of a crucial intermediate due to the upregulation of gluconeogenesis. Answer the following questions: A) What is that crucial citric acid cycle intermediate that has been depleted due to the upregulaton of gluconeogenesis? B) After lysine catabolism, do you expect its products to form substrates for gluconeogenesis? If so, why? If not, why not? C) During periods of starvation, which end-products of lysine catabolism can be used as an energy source to maintain brain function? In your answer, clearly indicate which answer belongs to which part.
Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter19: The Tricarboxylic Acid Cycle
Section: Chapter Questions
Problem 22P: Study Figure 19.18 and decide which of the following statements is false. Pyruvate dehydrogenase is...
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