Joe has classic hemophilia, an X-linked recessive disease. Could Joe have inherited the gene for this disease from the following people? Yes No a. His mother’s mother ____________ ____________ b. His mother’s father ____________ ____________ c. His father’s mother ____________ ____________ d. His father’s father ____________ ____________
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Joe has classic hemophilia, an X-linked recessive disease. Could Joe
have inherited the gene for this disease from the following people?
Yes No
a. His
mother’s
mother
____________ ____________
b. His
mother’s
father
____________ ____________
c. His
father’s
mother
____________ ____________
d. His
father’s
father
____________ ____________
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- Geneticists are concerned about three different genetic conditions present within their family. Achondroplasia is an autosomal dominant genetic disorder that results in short-limbed dwarfism. (A = achondroplasia allele; a = average height allele). Red-Green Color blindness is an X-linked recessive genetic disorder (Xc = color blindness allele; XC = normal color vision allele). The 7-year-old son has an autosomal recessive form of deafness. (h = deafness allele; H = normal hearing allele.) All three family members were karyotyped, and additional genetic testing was performed to determine the chromosomal location of the genes being studied. The figures below show the karyotypes of the mother and father with respect to the chromosomes containing the three genes mentioned above. Question: The couple’s 7-year-old son has all three of these genetic conditions (achondroplasia, color blindness and deafness). Taking into consideration the genotypes of his parents, what is the complete…Hereditary hemochromatosis is an autosomal recessive genetic disorder that causes the body to absorb too much iron from the diet. This excess iron is stored in the body's tissues and organs, particularly the skin, heart, liver, pancreas, and joints. Because humans cannot increase the excretion of iron, excess iron can overload and eventually damage tissues and organs. A man who had hemophilia (an X-linked recessive genetic disorder), married a woman who had no family history of hemophilia whatsoever. The couple had consulted a genetic counselor when they first contemplated having children due to concerns that their future children might have hemophilia. Genetic testing of both future parents revealed that the husband did, in fact, possess the Hemophilia A allele but his wife was completely normal with respect to hemophilia. Much to their shock, their first child, a daughter, had a mild blood clotting disorder. Karyotyping was performed to determine whether this daughter had an…A man who has color blindness and type O blood has children with a woman who has normal color vision and type AB blood. The woman’s father had color blindness. Color blindness is determined by an X-linked gene, and blood type is determined by an autosomal gene. a. What are the genotypes of the man and the woman? b. What proportion of their children will have color blindness and type B blood? c. What proportion of their children will have color blindness and type A blood? d. What proportion of their children will be color blind and have type AB blood?
- Hereditary hemochromatosis is an autosomal recessive genetic disorder that causes the body to absorb too much iron from the diet. This excess iron is stored in the body's tissues and organs, particularly the skin, heart, liver, pancreas, and joints. Because humans cannot increase the excretion of iron, excess iron can overload and eventually damage tissues and organs. Q. A man who had hemophilia (an X-linked recessive genetic disorder), married a woman who had no family history of hemophilia whatsoever. The couple had consulted a genetic counselor when they first contemplated having children due to concerns that their future children might have hemophilia. Genetic testing of both future parents revealed that the husband did, in fact, possess the Hemophilia A allele but his wife was completely normal with respect to hemophilia. Much to their shock, their first child, a daughter, had a mild blood clotting disorder. Karyotyping was performed to determine whether this daughter had an…Ichthyosis is a rare X-linked recessive disorder that is characterized by scaling of the skin around the neck and lower extremities. A young couple, Bart and Jenny, are expecting a child and are aware there might be a chance that their child could be affected by this disorder. Jenny (the wife) has ichthyosis, but Bart (her husband) is unaffected and completely normal with respect to the allele responsible for this disorder. A. Both Bart and Jenny were Biology majors as undergraduates. Knowing a little about the pattern of X-linked recessive inheritance, Bart and Jenny were concerned when ultrasound revealed that they would be having a son. However, genetic testing performed on the baby shortly after birth revealed that their newborn son, Mark, did not have ichthyosis. Explain how this could be the case, assuming that the gene responsible for ichthyosis is fully penetrant. If non-disjunction occurred, assume it happened in only one of the two parents, and during only one of the two…Y-linked Amelogenesis imperfecta (A), a congenital disorder that affects the formation of the teeth enamel making affected individuals at higher risk for dental cavities and related problems. X-linked dominant hypophosphatemia (H), a form of rickets or vitamin D deficiency that affects the bones which causes pain, osteoarthritis, and abnormal shapeabnormal shape. X-linked recessive progressive Duchenne muscular dystrophy (m), a muscular disorder, leading to an irreversible gradual wasting of skeletal muscles. Hannah, the same as her mom, is heterozygous for both X-linked traits. While her dad is suffering from both muscular dystrophy and hypophosphatemia. Hannah's husband, Joey has a mom suffering from musculardystrophy regardless of having normal bone conditions. His dad has been blessed with strong muscles and bones, however, he is suffering from amelogenesis imperfecta. What are the complete genotypes of each person?a. Joey's momb. Joey's dadc. Joeyd. Hannah's mome. Hannah's dad f.…
- Hemophilia is an X-linked recessive phenotype. Suppose a man who expresses the hemophilia phenotype has children with a woman who has the normal phenotype (and does not have a family history of hemophilia). If the couple have a son, what are the chances that he will have hemophilia? A) 50% B) 25% C) 0% D) 100%How did you identify Guinevere's genotype? is that trait recessive or dominant? What if Mike is type B, will it be possible that Guinevere's would still be type o?Jonah and Jana are siblings. Jonah has the genetic disorder cystic fibrosis, caused by inheriting one copy from each parent of a mutation in the CF gene. Jana does not have cystic fibrosis. Which of the following statements is/are true? (Select all that are true) a)Jana does not have the gene that when mutant causes cystic fibrosis. b)Jana has the gene that when mutant causes cystic fibrosis. c)Jana has two copies of the allele that causes cystic fibrosis. d)Jana does not have two copies of the allele that causes cystic fibrosis.