Many drugs administered to patients are actually primary amine (RNH2 derivatives).  These drugs may be very hydrophobic but are made water soluble by making them as mine salts.  A synthetic chemist treats the primary amine derivative with a strong acid like hydrochloric acid to make the amine salt.  Calculate the pH at the equivalence point in the titration of 75 mL of 0.10 M Methylamine with a 0.30 M HCl solution. The Ka for methylamine (CH3NH2) is 2.3X10-11.

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Chapter16: Acid-base Equilibria
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Problem 16.92QP: Sodium benzoate, NaC7H5O2, is used as a preservative in foods. Consider a 50.0-mL sample of 0.250 M...
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Many drugs administered to patients are actually primary amine (RNH2 derivatives).  These drugs may be very hydrophobic but are made water soluble by making them as mine salts.  A synthetic chemist treats the primary amine derivative with a strong acid like hydrochloric acid to make the amine salt.  Calculate the pH at the equivalence point in the titration of 75 mL of 0.10 M Methylamine with a 0.30 M HCl solution. The Ka for methylamine (CH3NH2) is 2.3X10-11.

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