Many metabolites are transported either actively or passively across mitochondrial outer and inner membrane, like metabolites involved in urea cycle. (A) Besides the metabolites involved in urea cycle, name other metabolites that are transported across the mitochondrial membranes and explain the biological importance for transporting those metabolites

Biochemistry
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Chapter1: Biochemistry: An Evolving Science
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Many metabolites are transported either actively or passively across mitochondrial outer
and inner membrane, like metabolites involved in urea cycle.
(A) Besides the metabolites involved in urea cycle, name other metabolites that are
transported across the mitochondrial membranes and explain the biological importance
for transporting those metabolites 
(B) Mice fed with amphipathic chemical W, K and V were found to lose body weight. It was
suspected that W and K affected mitochondrial functions. The amount of food
consumed by the mice was consistent throughout the experiment.
i. When mice were fed with W, all mitochondrial proteins were function properly. How
did W induce body weight loss? 
ii. When mice were fed with K, less complex III and IV were reduced in the electron
transport chains. Other mitochondrial proteins were function properly. How did K
induce body weight loss? 
iii. When mice were fed with V, adenosine monophosphates (AMPs) were accumulated in
cytosol and mitochondria while no enzyme was inhibited, and pH of mitochondria
remained the same. How did V induce body weight loss?

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