Match each of the enzymes involved in de novo pyrimidine synthesis with the correct description: _______ Dihydroorotate dehydrogenase _______ UMP synthase _______ Carbamoyl phosphate synthetase II _______ TMP synthase _______ CTP synthetase _______ Aspartate transcarbamoylase _______ PRPP synthetase (A) attaches an aspartate to an activated carbamoyl molecule (B) bifunctional enzyme that combines a nitrogenase pyrimidine ring to an activated ribose (C) catalyzes the formation of the activated ribose sugar (D) uses glutamine to add an amine to a preformed nucleotide (E) produces the first cyclic nitrogenase ring during de novo pyrimidine synthesis (F) combines bicarbonate and nitrogen from glutamine in the first step of pyrimidine ring synthesis (G) uses a folate derivative to add a methyl group to a preformed nucleotide

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter27: Metabolic Integration And Organ Specialization
Section: Chapter Questions
Problem 20P: Figure 27.3 illustrates the response of R (ATP-regenerating) and U (ATP-utilizing) enzymes to energy...
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Match each of the enzymes involved in de novo pyrimidine synthesis with the correct description:

_______ Dihydroorotate dehydrogenase _______ UMP synthase
_______ Carbamoyl phosphate synthetase II _______ TMP synthase

_______ CTP synthetase
_______ Aspartate transcarbamoylase _______ PRPP synthetase

(A) attaches an aspartate to an activated carbamoyl molecule
(B) bifunctional enzyme that combines a nitrogenase pyrimidine ring to an activated ribose
(C) catalyzes the formation of the activated ribose sugar
(D) uses glutamine to add an amine to a preformed nucleotide
(E) produces the first cyclic nitrogenase ring during de novo pyrimidine synthesis
(F) combines bicarbonate and nitrogen from glutamine in the first step of pyrimidine ring synthesis (G) uses a folate derivative to add a methyl group to a preformed nucleotide

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