All of the following is correct about folate and vitamin B12 involvement in resynthesis of methionine from homocysteine except: Cobalamin acts as a methyl donor by giving the methyl group to 5-methyl THF Methylcobalamin give a methyl group to homocysteine to form methionine and reform cobalamin 5, 10-methylene THF is converted to 5-methyl THF by methylene THF reductase The involvement of folate and vitamin B12occurs in the cytosol.

All of the following is correct about folate and vitamin B12 involvement in resynthesis of methionine from homocysteine except: Cobalamin acts as a methyl donor by giving the methyl group to 5-methyl THF Methylcobalamin give a methyl group to homocysteine to form methionine and reform cobalamin 5, 10-methylene THF is converted to 5-methyl THF by methylene THF reductase The involvement of folate and vitamin B12occurs in the cytosol.

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter17: Metabolism: An Overview

Section: Chapter Questions

Problem 12P: How Do Vitamin-Derived Coenzymes Aid Metabolism? What chemical functionality is provided to enzyme...

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The primary route of carbon entry into the tetrahydrofolate (THF) pool is via the serine hydroxymethyl transferase reaction. Which of the following is required to convert that initial form of the THF into the form that can donate carbons to de novo purine synthesis? (A) Glycine (B) FAD (C) Water (D) B12 (E) B6 plz type no hand written a short note plz
Match each of the enzymes involved in de novo pyrimidine synthesis with the correct description: _______ Dihydroorotate dehydrogenase _______ UMP synthase_______ Carbamoyl phosphate synthetase II _______ TMP synthase _______ CTP synthetase_______ Aspartate transcarbamoylase _______ PRPP synthetase (A) attaches an aspartate to an activated carbamoyl molecule(B) bifunctional enzyme that combines a nitrogenase pyrimidine ring to an activated ribose(C) catalyzes the formation of the activated ribose sugar(D) uses glutamine to add an amine to a preformed nucleotide(E) produces the first cyclic nitrogenase ring during de novo pyrimidine synthesis(F) combines bicarbonate and nitrogen from glutamine in the first step of pyrimidine ring synthesis (G) uses a folate derivative to add a methyl group to a preformed nucleotide
All of the following products of biosynthesis are nitrogen-rich tetrapyrrole structures that can be synthesized from Krebs cycle intermediates (in some plants, animals, or bacteria), with the exception of: triglyceride molecules chlorophyll b molecules vitamin B12 molecules chlorophyll a molecules heme molecules Identify the Krebs cycle enzyme that consumes a six-carbon substrate molecule, producing a five-carbon product molecule along with NADH, and one molecule of CO2. succinyl CoA synthetase a-ketoglutarate dehydrogenase malate dehydrogenase isocitrate dehydrogenase citrate synthase
Chemolithotrophs meet their energy needs by oxidizing organic food molecules. True False Which of the following events does not occur during the energy-investment phase of glycolysis? Hexokinase catalyzes the transfer of a phosphate group from ATP to glucose to form glucose-6-phosphate. Phosphofructokinase catalyzes the isomerization of glucose-6-phosphate to fructose-6-phosphate. Fructose-bisphosphate aldolase cleaves Fructose-1,6-bisphosphate into two different three-carbon sugars. Dihydroxyacetone phosphate can be converted to glyceraldehyde-3-phosphate with the help of the enzyme triose phosphate isomerase.
The glycine cleavage system is a group of four enzymes that together catalyze the following reaction: Use the following information to determine the sequence of reactions carried out by the glycine cleavage system:a. The first enzyme is a PLP-requiring decarboxylase.b. The second enzyme is aminomethyltransferase. This enzyme has a lipoate coenzyme.c. The third enzyme synthesizes N5,N10-methylene-THF and also forms +NH4.d. The fourth enzyme is an FAD-requiring enzyme.e. The cleavage system also requires NAD+ .
Which one of the following best describes the role of water in the reaction that is catalyzed by chymotrypsin? choose the best answer based on your coverage. Water forms several H-bonds with the transition state to stabilize it. Water deprotonates the Ser, converting Ser into a strong nucleophile. Water is a product of the reaction. His deprotonates the water, converting the water into a strong nucleophile. Water serves as a catalyst, being consumed and then regenerated in the reaction.
What are the donor atoms involved in Aspartame-Cu(II) binding? A) Nitrogen atom of alpha amine group of Aspartic acid and an oxygen atom of alpha carboxyilic acid group of Aspartic acid B) Nitrogen atom of alpha amine group of Phenyl alanine methyl ester and an oxygen atom of alpha carboxyilic acid group of Aspartic acid C) Nitrogen atom of alpha amine group of Aspartic acid and an oxygen atom of alpha carboxyilic acid group of Phenyl alanine methyl ester D) Oxygen atoms of the dipeptide Aspartame E) Nitrogen atom of alpha amine group of Aspartic acid and an oxygen atom of carboxyilic acid group of the R group of Aspartic acid
Which of the following statements about folic acid is not true? a. Folic acid is activated by folate synthase. b. Folic acid structure contains a pteridine ring and para-amino benzoic acid. c. NADPH is required in the reactions activating folic acid. d. Tetrahydrofolate is the biologically active derivative of folic acid.
Why does FAD accepts 2 protons in dehydration of succinate to fumarate? Why dont NAD molecules participate in this reaction?
Can you please pick the right answer in each parentheses? The pentose phosphate pathway provides a number of critical functions including ["production of ribose-5-phosphate", "production of NADH"] that is vital for ["synthesis of nucleotides and coenzymes", "oxidative phosphorylation"] . This pathway is divided into oxidative and non-oxidative steps. The latter steps ["are involved in the conversion of various sugar phopshates, so called ["carbon shuffle reactions"", "are directly involved in NADPH production"] . If ["NADP+", "NAD+"] levels are high, flux through the pentose phosphate pathway is promoted by allosteric regulation of glucose-6-phosphate dehydrogenase. If reducing equivalents derived form the pentose phosphate pathway are high, glucose-6-phosphate is directed toward ["a phosphatase and then export from the cell", "glycolysis"] .
Specify the type of carbon unit that is transferred in one-carbon metabolism by each of the following molecules: 5 10 a. N , N -methylene THF b. serine c. choline d. S-adenosylmethionine
Show how you would accomplish the following synthetic transformations. Show all intermediates.(a) 2,2@dibromobutane ¡ but@1@yne (b) 2,2@dibromobutane ¡ but@2@yne(c) but@1@yne ¡ oct@3@yne (d) trans@hex@2@ene ¡ hex@2@yne(e) 2,2@dibromohexane ¡ hex@1@yne (f) cyclodecyne ¡ cis@cyclodecene(g) cyclodecyne ¡ trans@cyclodecene (h) hex@1@yne ¡ hexan@2@one, CH3COCH2CH2CH2CH3(i) hex@1@yne ¡ hexanal, CH3(CH2)4CHO (j) trans@hex@2@ene ¡ cis@hex@2@ene