Michaelis-Menten kinetics is sometimes referred to as “saturation” kinetics. Why? 22. Give the Michaelis-Menten equation and define each term in it. Does this equation apply to all enzymes? If not, to which kind does it not apply? 23. Methanol (wood alcohol) is highly toxic because it is converted to formaldehyde in a reaction
Catalysis and Enzymatic Reactions
Catalysis is the kind of chemical reaction in which the rate (speed) of a reaction is enhanced by the catalyst which is not consumed during the process of reaction and afterward it is removed when the catalyst is not used to make up the impurity in the product. The enzymatic reaction is the reaction that is catalyzed via enzymes.
Lock And Key Model
The lock-and-key model is used to describe the catalytic enzyme activity, based on the interaction between enzyme and substrate. This model considers the lock as an enzyme and the key as a substrate to explain this model. The concept of how a unique distinct key only can have the access to open a particular lock resembles how the specific substrate can only fit into the particular active site of the enzyme. This is significant in understanding the intermolecular interaction between proteins and plays a vital role in drug interaction.
21. Michaelis-Menten kinetics is sometimes referred to as “saturation” kinetics. Why?
22. Give the Michaelis-Menten equation and define each term in it. Does this equation apply to
all enzymes? If not, to which kind does it not apply?
23. Methanol (wood alcohol) is highly toxic because it is converted to formaldehyde in a reaction
catalyzed by the enzyme alcohol dehydrogenase:
NAD+ + methanol → NADH + H+ + formaldehyde
Part of the medical treatment for methanol poisoning is to administer ethanol (ethyl alcohol) in amounts
large enough to cause intoxication under normal circumstances. Explain this in terms of what you know
about examples of enzymatic reactions.
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