MicroRNAs are small RNA molecules that bind to the 3′ end of mRNA and suppress translation . Some eukaryotic mRNAs have internal ribosome-binding sites downstream of the 5′ cap, where ribosomes normally bind. In one investigation, miRNAs did not suppress translation by ribosomes that had attached to internal ribosomebinding sites (R. S. Pillai et al. 2005. Science 309:1573–1576). What does this finding suggest about how miRNAs suppress translation?
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
MicroRNAs are small RNA molecules that bind to the 3′ end of
mRNA and suppress translation . Some eukaryotic
mRNAs have internal ribosome-binding sites downstream of the 5′ cap,
where ribosomes normally bind. In one investigation, miRNAs did not
suppress translation by ribosomes that had attached to internal ribosomebinding
sites (R. S. Pillai et al. 2005. Science 309:1573–1576). What
does this finding suggest about how miRNAs suppress translation?
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