Asked Oct 2, 2019
  1. Mutations in genes that affect meiosis have been identified in many different model organisms.  Most of these mutations result in aneuploidy of more than a single chromosome and are nearly sterile.  Explain why this is the case.

Expert Answer

Step 1

Meiosis is the process of division of a cell in which four daughter cells are produced. The resulting daughter cells also have half the number of ploidy (set of chromosomes) as that in parental cell. Defects occurring during the process of crossing over (exchange of chromosomal segments of homologous pairs during meiosis I) results in unequal distribution of chromosomes resulting in aneuploidy (a condition in which the daughter cell may have extra or less number of chromosomes as than in normal case).

Step 2

Every living organism has genetic material that controls every action performed by the cell. Similarly, meiosis is controlled by set of genes. Mutation of any of such genes controlling the process of crossing over and equal segregation of chromosomes, results in conditions like aneuploidy (one or more pair of chromosomes or part of chromosome is extra or less).

When chromosomes that are associated with fertility (not only controlled by sex chromosomes but other autosomes too) of the organism are segregated abnormally, repro...

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