NO Date The Synttesized alicylic ocid fron Kolbe - Schmitt reachion con be Fur ther readted with ecers acetic anhydnide to produce ace tylsalicafie aad (aspnin) as choun belbw ) Rotionalize why acehic anhycride wr cuseé instead of acetic aad. 2) Why is there a nood to add acetic anhy dnde in exces:
NO Date The Synttesized alicylic ocid fron Kolbe - Schmitt reachion con be Fur ther readted with ecers acetic anhydnide to produce ace tylsalicafie aad (aspnin) as choun belbw ) Rotionalize why acehic anhycride wr cuseé instead of acetic aad. 2) Why is there a nood to add acetic anhy dnde in exces:
Chapter21: Carboxylic Acid Derivatives: Nucleophilic Acyl Substitution Reactions
Section21.SE: Something Extra
Problem 81AP
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Transcribed Image Text:NO
Date
The Synttesized galicaylic ocid from Kole -
can be Fuur ther eaced with excess acetic anhydnide
o produce ace tylsalicgie as shown below
schmitt reachon
anhycride
to produce aad (aspinin
aad lasanin)
1) fationalize why acetic anhydride
won cescé instead
of acetic aad.
2) Why c anhy dnde in txces.
Is there a ned to add acetic
excess
Transcribed Image Text:`NH2
`OH
Salicylamide
но.
H2SO4
Scheme 3. Synthesis of Aspirin
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