Now let's consider histidine as a free amino acid in aqueous solution.a) Draw the most likely structure of histidine under biochemical standard stateconditions.b) Given that free histidine has the following three pKa values, assign each to itscorresponding acidic hydrogen or conjugate base in your structure from part a).pK1 = 1.7,pKa2 = 6.0,pK23 = 9.1c)For each pKa, give the corresponding expression for the equilibrium constant.It helps to write out the chemical equation for each.

The structure of histidine at standard biochemical condition is given below It exist in its…

Now let's consider histidine as a free amino acid in aqueous solution. Draw the most likely structure of histidine under biochemical standard state conditions. Given that free histidine has the following three pK, values, assign each to its corresponding acidic hydrogen or conjugate base in your structure from part a). pK1 = 1.7, pK22 = 6.0, pK33 = 9.1 For each pKa, give the corresponding expression for the equilibrium constant.

Now let's consider histidine as a free amino acid in aqueous solution. Draw the most likely structure of histidine under biochemical standard state conditions. Given that free histidine has the following three pK, values, assign each to its corresponding acidic hydrogen or conjugate base in your structure from part a). pK1 = 1.7, pK22 = 6.0, pK33 = 9.1 For each pKa, give the corresponding expression for the equilibrium constant.

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter26: Biomolecules: Amino Acids, Peptides, And Proteins

Section26.SE: Something Extra

Problem 57AP: Oxytocin, a nonapeptide hormone secreted by the pituitary gland, functions by stimulating uterine...

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In the case of serine, threonine and tyrosine they have the -OH group in their residue. I'm wondering even though all of them has the -OH groups in their residue. but only the tyrosine has the pKa value with the -OH grouup.
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